Mei Yang1, Jules Mamy2, Liang Zhou2, Yan-Hui Liao3, Qiang Wang4, Vasish Seewoobudul3, Shui-Yuan Xiao5, Wei Hao6. 1. Department of Social Medicine, School of Public Health, Central South University, Changsha, China; Mental Health Institute, Second Xiangya Hospital, Central South University, Changsha, China. 2. Department of Social Medicine, School of Public Health, Central South University, Changsha, China. 3. Mental Health Institute, Second Xiangya Hospital, Central South University, Changsha, China. 4. Department of Psychiatry, West China Hospital, Sichuan University, Chengdu, China. 5. Department of Social Medicine, School of Public Health, Central South University, Changsha, China. Electronic address: xiaosy@live.com. 6. Mental Health Institute, Second Xiangya Hospital, Central South University, Changsha, China. Electronic address: weihao57@gmail.com.
Abstract
BACKGROUND: Little is known about gender difference in correlates of antisocial personality disorder (ASPD) among drug users. OBJECTIVE: To detect gender difference in correlates of ASPD in a Chinese heroin dependent sample. METHODS: Structured interviews were conducted among 882 heroin dependent users in two compulsory isolation settings in Changsha, China. Descriptive statistics were employed to report sample characteristics by gender. Bivariate relationships were examined between co-occurring ASPD and variables measuring demographic, drug use, and psychiatric co-morbidities. Multivariate logistic regressions with stepwise forward method were conducted to determine independent predictors for co-occurring ASPD. All analyses examining correlates of co-occurring ASPD were conducted for the total, the male and the female participants respectively to detect both the common and the unique correlates of ASPD by gender. RESULTS: Of the total participants, 41.4% (54.2% of males and 15.4% of females) met the DSM-IV criteria of ASPD. For male participants, lower educational level, unemployment, unmarried, younger age at first heroin use, previous history of compulsory treatment, larger amounts of heroin used per day and poly-drug abuse during past month before admission, as well as psychiatric co-morbidities of lifetime major depressive disorder and borderline personality disorder were independent predictors for co-occurring ASPD; while for female participants, only three variables: younger age at first heroin use, paranoid personality disorder and borderline personality disorder were independent predictors for co-occurring ASPD. CONCLUSIONS: Gender differences in prevalence and correlates of ASPD among heroin dependent users were detected. The findings highlight a need for gender-specific interventions.
BACKGROUND: Little is known about gender difference in correlates of antisocial personality disorder (ASPD) among drug users. OBJECTIVE: To detect gender difference in correlates of ASPD in a Chinese heroin dependent sample. METHODS: Structured interviews were conducted among 882 heroin dependent users in two compulsory isolation settings in Changsha, China. Descriptive statistics were employed to report sample characteristics by gender. Bivariate relationships were examined between co-occurring ASPD and variables measuring demographic, drug use, and psychiatric co-morbidities. Multivariate logistic regressions with stepwise forward method were conducted to determine independent predictors for co-occurring ASPD. All analyses examining correlates of co-occurring ASPD were conducted for the total, the male and the female participants respectively to detect both the common and the unique correlates of ASPD by gender. RESULTS: Of the total participants, 41.4% (54.2% of males and 15.4% of females) met the DSM-IV criteria of ASPD. For male participants, lower educational level, unemployment, unmarried, younger age at first heroin use, previous history of compulsory treatment, larger amounts of heroin used per day and poly-drug abuse during past month before admission, as well as psychiatric co-morbidities of lifetime major depressive disorder and borderline personality disorder were independent predictors for co-occurring ASPD; while for female participants, only three variables: younger age at first heroin use, paranoid personality disorder and borderline personality disorder were independent predictors for co-occurring ASPD. CONCLUSIONS: Gender differences in prevalence and correlates of ASPD among heroin dependent users were detected. The findings highlight a need for gender-specific interventions.
Authors: Teerayuth Rungnirundorn; Viroj Verachai; Joel Gelernter; Robert T Malison; Rasmon Kalayasiri Journal: J Addict Med Date: 2017 Jan/Feb Impact factor: 3.702