A Duruflé-Tapin1, A Colin2, B Nicolas1, C Lebreton3, F Dauvergne4, P Gallien5. 1. Pôle de médecine physique et réadaptation Saint-Hélier, 54, rue Saint-Hélier, 35000 Rennes, France; Réseau Breizh-PC, pôle de médecine physique et réadaptation Saint-Hélier, 54, rue Saint-Hélier, 35000 Rennes, France. 2. Réseau Breizh-PC, pôle de médecine physique et réadaptation Saint-Hélier, 54, rue Saint-Hélier, 35000 Rennes, France. 3. École des hautes études en santé publique, avenue du Professeur-Léon-Bernard, CS 74312, 35043 Rennes, France. 4. Pôle de médecine physique et réadaptation Saint-Hélier, 54, rue Saint-Hélier, 35000 Rennes, France. 5. Pôle de médecine physique et réadaptation Saint-Hélier, 54, rue Saint-Hélier, 35000 Rennes, France; Réseau Breizh-PC, pôle de médecine physique et réadaptation Saint-Hélier, 54, rue Saint-Hélier, 35000 Rennes, France. Electronic address: pc.gallien@wanadoo.fr.
Abstract
AIM: To investigate causes of death and age at death in cerebral palsy subjects compared with the general population. METHOD: Analysis of data supplied by the centre of epidemiology on the medical causes of death within the National Institute of Health and Medical Research in France was conducted. Three thousand and thirty-one death certificates indicating a diagnosis of cerebral palsy (ICD-10 code G80) were reported between 2000 and 2008. RESULTS: Median age at death was between 45-54 years and principal cause of death (24%) comprised the category "symptoms, signs, and abnormal results of clinical and laboratory tests, not classified elsewhere". Of these, 66% were related to the circulatory and respiratory systems. "Diseases of the respiratory system" were the second most common cause of death (19% compared with 6% in the French general population). The third most common cause of death was "diseases of the circulatory system" (15% compared with 29% in the French general population). While deaths caused by tumour pathologies in the general population are the most common cause of deaths, these represented only 7% of deaths in subjects with cerebral palsy. INTERPRETATION: These results concur with other published data, i.e. subjects with cerebral palsy die younger than the French general population, and the principal causes of death are respiratory and circulatory problems. This study emphasises the importance of access to epidemiological data about the French cerebral palsy population.
AIM: To investigate causes of death and age at death in cerebral palsy subjects compared with the general population. METHOD: Analysis of data supplied by the centre of epidemiology on the medical causes of death within the National Institute of Health and Medical Research in France was conducted. Three thousand and thirty-one death certificates indicating a diagnosis of cerebral palsy (ICD-10 code G80) were reported between 2000 and 2008. RESULTS: Median age at death was between 45-54 years and principal cause of death (24%) comprised the category "symptoms, signs, and abnormal results of clinical and laboratory tests, not classified elsewhere". Of these, 66% were related to the circulatory and respiratory systems. "Diseases of the respiratory system" were the second most common cause of death (19% compared with 6% in the French general population). The third most common cause of death was "diseases of the circulatory system" (15% compared with 29% in the French general population). While deaths caused by tumour pathologies in the general population are the most common cause of deaths, these represented only 7% of deaths in subjects with cerebral palsy. INTERPRETATION: These results concur with other published data, i.e. subjects with cerebral palsy die younger than the French general population, and the principal causes of death are respiratory and circulatory problems. This study emphasises the importance of access to epidemiological data about the French cerebral palsy population.
Authors: Jakub S Gąsior; Antonio Roberto Zamunér; Luiz Eduardo Virgilio Silva; Craig A Williams; Rafał Baranowski; Jerzy Sacha; Paulina Machura; Wacław Kochman; Bożena Werner Journal: J Clin Med Date: 2020-04-16 Impact factor: 4.241
Authors: Jennifer M Ryan; Mark D Peterson; Nicola Ryan; Kimberley J Smith; Neil E O'connell; Silvia Liverani; Nana Anokye; Christina Victor; Elizabeth Allen Journal: Dev Med Child Neurol Date: 2019-02-06 Impact factor: 5.449