Literature DB >> 24341482

Quinoline-based two-photon fluorescent probe for nitric oxide in live cells and tissues.

Xiaohu Dong1, Cheol Ho Heo, Shiyu Chen, Hwan Myung Kim, Zhihong Liu.   

Abstract

A two-photon fluorescent probe (QNO) for nitric oxide is reported. The probe is designed with a photoinduced electron transfer (PeT) mechanism and shows 12-fold fluorescence enhancement toward NO. Adopting a quinoline derivative as the fluorophore, QNO has a large two-photon action cross section value of 52 GM and long-wavelength emission. It also features high selectivity, low cytotoxicity, and pH insensitivity. By utilizing two-photon microscopy (TPM), QNO can detect NO in live cells and live tissues at a depth of 90-180 μm.

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Year:  2013        PMID： 24341482     DOI： 10.1021/ac403226h

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  12 in total

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5.  A Two-Photon Ratiometric Fluorescent Probe for Imaging of Hydrogen Peroxide Levels in Rat Organ Tissues.

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6.  An N-nitrosation reactivity-based two-photon fluorescent probe for the specific in situ detection of nitric oxide.

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Journal:  Chem Sci       Date:  2017-04-20       Impact factor: 9.825

7.  Iridium-based probe for luminescent nitric oxide monitoring in live cells.

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9.  Theoretical Design of a Two-Photon Fluorescent Probe for Nitric Oxide with Enhanced Emission Induced by Photoninduced Electron Transfer.

Authors:  Yujin Zhang; Jiancai Leng; Wei Hu
Journal:  Sensors (Basel)       Date:  2018-04-25       Impact factor: 3.576

10.  Engineering a nanolab for the determination of lysosomal nitric oxide by the rational design of a pH-activatable fluorescent probe.

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Journal:  Chem Sci       Date:  2015-11-30       Impact factor: 9.825
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