STUDY OBJECTIVES: The objective of this study was to identify if hyperarousal is a 24-hour phenomenon in insomnia by comparing sleep during napping between good sleepers (GS) and Insomnia sufferers (INS) (subdivided into paradoxical "PARA-I" and psychophysiological "PSY-I") following a mentally challenging battery of cognitive tests. DESIGN: Cross-sectional comparisons of GS, PSY-I, and PARA-I. SETTING: Participants slept for 4 consecutive nights in the laboratory where PSG was recorded. Upon awakening on mornings 2 and 3, cognitive testing (lasting 90-120 min) was administered, followed by a 20-minute nap. PARTICIPANTS: Fourteen PSY-I, 12 PARA-I, and 23 GS completed the study, comprising home questionnaires, clinical interviews, night PSG recordings, cognitive testing, and nap PSG recordings. All participants were between 25 and 50 years of age and met inclusion criteria for PSY-I, PARA-I, or GS. INTERVENTIONS: N/A. MEASUREMENTS AND RESULTS: On objective nap parameters, GS had a longer total sleep time (TST; p = 0.008) and better sleep efficiency (SE; p = 0.009), than PSY-I and PARA-I, and both groups of INS were awake significantly longer than GS (p = 0.003). Also, PARA-I took significantly more time than GS to fall asleep (p = 0.014). Subjectively reported sleepiness was comparable across the three groups. Positive relationships were observed between SE over the night and SE over the nap the following day. CONCLUSIONS: Results show that GS sleep better than INS during naps following prolonged cognitive testing, suggesting that, in INS, hyperarousal predominates over mental fatigue resulting from these tests. These results may parallel what is observed at night when INS experience increased cognitive load but are unable to fall asleep.
STUDY OBJECTIVES: The objective of this study was to identify if hyperarousal is a 24-hour phenomenon in insomnia by comparing sleep during napping between good sleepers (GS) and Insomnia sufferers (INS) (subdivided into paradoxical "PARA-I" and psychophysiological "PSY-I") following a mentally challenging battery of cognitive tests. DESIGN: Cross-sectional comparisons of GS, PSY-I, and PARA-I. SETTING:Participants slept for 4 consecutive nights in the laboratory where PSG was recorded. Upon awakening on mornings 2 and 3, cognitive testing (lasting 90-120 min) was administered, followed by a 20-minute nap. PARTICIPANTS: Fourteen PSY-I, 12 PARA-I, and 23 GS completed the study, comprising home questionnaires, clinical interviews, night PSG recordings, cognitive testing, and nap PSG recordings. All participants were between 25 and 50 years of age and met inclusion criteria for PSY-I, PARA-I, or GS. INTERVENTIONS: N/A. MEASUREMENTS AND RESULTS: On objective nap parameters, GS had a longer total sleep time (TST; p = 0.008) and better sleep efficiency (SE; p = 0.009), than PSY-I and PARA-I, and both groups of INS were awake significantly longer than GS (p = 0.003). Also, PARA-I took significantly more time than GS to fall asleep (p = 0.014). Subjectively reported sleepiness was comparable across the three groups. Positive relationships were observed between SE over the night and SE over the nap the following day. CONCLUSIONS: Results show that GS sleep better than INS during naps following prolonged cognitive testing, suggesting that, in INS, hyperarousal predominates over mental fatigue resulting from these tests. These results may parallel what is observed at night when INS experience increased cognitive load but are unable to fall asleep.
Authors: Johan Wuyts; Elke De Valck; Marie Vandekerckhove; Nathalie Pattyn; Arnoud Bulckaert; Daniel Berckmans; Bart Haex; Johan Verbraecken; Raymond Cluydts Journal: Int J Psychophysiol Date: 2011-09-29 Impact factor: 2.997
Authors: J B Williams; M Gibbon; M B First; R L Spitzer; M Davies; J Borus; M J Howes; J Kane; H G Pope; B Rounsaville Journal: Arch Gen Psychiatry Date: 1992-08
Authors: Ana Ribeiro; Rachel Gabriel; Bernardo Garcia; Casey Cuccio; William Aqeel; Alejandro Moreno; Colby Landeen; Arlene Hurley; Neil Kavey; Donald Pfaff Journal: Proc Natl Acad Sci U S A Date: 2022-06-13 Impact factor: 12.779
Authors: E Garcia-Rill; B Luster; S D'Onofrio; S Mahaffey; V Bisagno; F J Urbano Journal: J Neural Transm (Vienna) Date: 2015-11-23 Impact factor: 3.575
Authors: Christine M Walsh; Leslie Ruoff; Kathleen Walker; Alaisa Emery; Jonathan Varbel; Elissaios Karageorgiou; Phi N Luong; Irida Mance; Hilary W Heuer; Adam L Boxer; Lea T Grinberg; Joel H Kramer; Bruce L Miller; Thomas C Neylan Journal: Sleep Date: 2017-11-01 Impact factor: 5.849