BACKGROUND: Musculoskeletal involvement in human immunodeficiency virus (HIV) infected patients are important disease manifestations, responsible for increased morbidity and also decreased quality of life. OBJECTIVES: To study the spectrum of different musculoskeletal involvement in HIV infected patients and its impact on quality of life. PATIENTS AND METHODS: Three hundred (n = 300) HIV-1 reactive patients were evaluated in respect to different musculoskeletal involvement including the quality of life from January 2010 to January 2011. RESULTS: Male to female ratio was 11:1 with a mean age of 35 (±6.4) years and mean duration of the disease was 3 (±1.54) years. Majority of cases were truck drivers, motel workers, and jewelry workers. Musculoskeletal disorders were observed in a total of 190 cases (63.33%). The spectrum of musculoskeletal involvement was: Body ache in 140 (46.7%), arthralgia in 80 (26.7%), mechanical low back pain in 25 (8.3%), osteoporosis in 20 (6.7%), painful articular syndrome in 10 (3.3%), hypertrophic osteoarthropathy in two (0.7%), pyomyositis in two (0.7%), osteomyelitis in one (0.3%), and avascular bone necrosis in one patient (0.3%). Rheumatologic disorders associated were: Reactive arthritis in seven (2.3%), fibromyalgia in four (1.3%), septic arthritis in three (1%), acute gout in three (1%), spondyloarthropathy in two (0.7%), rheumatoid arthritis in two (0.7%), dermatomyositis in one (0.3%), and systemic lupus erythematosus (SLE) in one patient (0.3%). But HIV associated arthritis and diffuse infiltrative lymphocytosis syndrome (DILS) were not detected. Most of the patients had decreased quality of life. CONCLUSIONS: Musculoskeletal involvement was common in HIV patients causing increased morbidity, so early detection and timely intervention is essential to improve quality of life.
BACKGROUND:Musculoskeletal involvement in human immunodeficiency virus (HIV) infectedpatients are important disease manifestations, responsible for increased morbidity and also decreased quality of life. OBJECTIVES: To study the spectrum of different musculoskeletal involvement in HIV infectedpatients and its impact on quality of life. PATIENTS AND METHODS: Three hundred (n = 300) HIV-1 reactive patients were evaluated in respect to different musculoskeletal involvement including the quality of life from January 2010 to January 2011. RESULTS: Male to female ratio was 11:1 with a mean age of 35 (±6.4) years and mean duration of the disease was 3 (±1.54) years. Majority of cases were truck drivers, motel workers, and jewelry workers. Musculoskeletal disorders were observed in a total of 190 cases (63.33%). The spectrum of musculoskeletal involvement was: Body ache in 140 (46.7%), arthralgia in 80 (26.7%), mechanical low back pain in 25 (8.3%), osteoporosis in 20 (6.7%), painful articular syndrome in 10 (3.3%), hypertrophic osteoarthropathy in two (0.7%), pyomyositis in two (0.7%), osteomyelitis in one (0.3%), and avascular bone necrosis in one patient (0.3%). Rheumatologic disorders associated were: Reactive arthritis in seven (2.3%), fibromyalgia in four (1.3%), septic arthritis in three (1%), acute gout in three (1%), spondyloarthropathy in two (0.7%), rheumatoid arthritis in two (0.7%), dermatomyositis in one (0.3%), and systemic lupus erythematosus (SLE) in one patient (0.3%). But HIV associated arthritis and diffuse infiltrative lymphocytosis syndrome (DILS) were not detected. Most of the patients had decreased quality of life. CONCLUSIONS:Musculoskeletal involvement was common in HIVpatients causing increased morbidity, so early detection and timely intervention is essential to improve quality of life.
Entities:
Keywords:
Human immunodeficiency virus infection; musculoskeletal disorder; quality of life
Authors: A Berman; L R Espinoza; J D Diaz; J L Aguilar; T Rolando; F B Vasey; B F Germain; R F Lockey Journal: Am J Med Date: 1988-07 Impact factor: 4.965
Authors: S M Forster; M H Seifert; A C Keat; I F Rowe; B J Thomas; D Taylor-Robinson; A J Pinching; J R Harris Journal: Br Med J (Clin Res Ed) Date: 1988-06-11
Authors: Louise Schade Berg; James J Young; Deborah Kopansky-Giles; Stefan Eberspaecher; Geoff Outerbridge; Eric L Hurwitz; Jan Hartvigsen Journal: Curr Med Sci Date: 2022-01-28