Literature DB >> 24339048

Synthesis of silk fibroin micro- and submicron spheres using a co-flow capillary device.

Alexander N Mitropoulos1, Giovanni Perotto, Sunghwan Kim, Benedetto Marelli, David L Kaplan, Fiorenzo G Omenetto.   

Abstract

A custom-made co-flow capillary device is used to synthesize monodisperse silk fibroin micro- and submicron-spheres with diameters tunable over a wide range of sizes. A model drug release is examined and control of degradation kinetics is obtained by changing sphere diameter.
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  microfluidics; microspheres; nanoparticles; silk

Year:  2013        PMID： 24339048     DOI： 10.1002/adma.201304244

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  16 in total

1.  Programming function into mechanical forms by directed assembly of silk bulk materials.

Authors:  Benedetto Marelli; Nereus Patel; Thomas Duggan; Giovanni Perotto; Elijah Shirman; Chunmei Li; David L Kaplan; Fiorenzo G Omenetto
Journal:  Proc Natl Acad Sci U S A       Date:  2016-12-27       Impact factor: 11.205

Review 2.  Controlled release from recombinant polymers.

Authors:  Robert Price; Azadeh Poursaid; Hamidreza Ghandehari
Journal:  J Control Release       Date:  2014-06-21       Impact factor: 9.776

3.  Delivery of chemotherapeutics using spheres made of bioengineered spider silks derived from MaSp1 and MaSp2 proteins.

Authors:  Katarzyna Jastrzebska; Anna Florczak; Kamil Kucharczyk; Yinnan Lin; Qin Wang; Andrzej Mackiewicz; David L Kaplan; Hanna Dams-Kozlowska
Journal:  Nanomedicine (Lond)       Date:  2018-01-17       Impact factor: 5.307

4.  Triptolide and celastrol loaded silk fibroin nanoparticles show synergistic effect against human pancreatic cancer cells.

Authors:  Baoyue Ding; Md Arif Wahid; Zhijun Wang; Chen Xie; Arvind Thakkar; Sunil Prabhu; Jeffrey Wang
Journal:  Nanoscale       Date:  2017-08-17       Impact factor: 7.790

Review 5.  Fiber-Based Biopolymer Processing as a Route toward Sustainability.

Authors:  Chunmei Li; Junqi Wu; Haoyuan Shi; Zhiyu Xia; Jugal Kishore Sahoo; Jingjie Yeo; David L Kaplan
Journal:  Adv Mater       Date:  2021-10-13       Impact factor: 30.849

Review 6.  Deconstruction and Reassembly of Renewable Polymers and Biocolloids into Next Generation Structured Materials.

Authors:  Blaise L Tardy; Bruno D Mattos; Caio G Otoni; Marco Beaumont; Johanna Majoinen; Tero Kämäräinen; Orlando J Rojas
Journal:  Chem Rev       Date:  2021-08-20       Impact factor: 72.087

7.  Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.

Authors:  Onur Hasturk; Jordan A Smiley; Miles Arnett; Jugal Kishore Sahoo; Cristian Staii; David L Kaplan
Journal:  Adv Healthc Mater       Date:  2022-06-22       Impact factor: 11.092

8.  Silk micrococoons for protein stabilisation and molecular encapsulation.

Authors:  Ulyana Shimanovich; Francesco S Ruggeri; Erwin De Genst; Jozef Adamcik; Teresa P Barros; David Porter; Thomas Müller; Raffaele Mezzenga; Christopher M Dobson; Fritz Vollrath; Chris Holland; Tuomas P J Knowles
Journal:  Nat Commun       Date:  2017-07-19       Impact factor: 14.919

9.  Doxorubicin loaded nanodiamond-silk spheres for fluorescence tracking and controlled drug release.

Authors:  Asma Khalid; Alexander N Mitropoulos; Benedetto Marelli; Snjezana Tomljenovic-Hanic; Fiorenzo G Omenetto
Journal:  Biomed Opt Express       Date:  2015-12-15       Impact factor: 3.732

10.  Microporous drug-eluting large silk particles through cryo-granulation.

Authors:  Ilya A Rodionov; Nadia Abdullah; David L Kaplan
Journal:  Adv Eng Mater       Date:  2019-04-18       Impact factor: 3.862
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