Literature DB >> 24338485

Prospective clinical study on digital nerve repair with collagen nerve conduits and review of literature.

Joern Andreas Lohmeyer1, Yasmin Kern1, Daniel Schmauss1, Felix Paprottka1, Felix Stang2, Frank Siemers2, Peter Mailaender2, Hans-Guenther Machens1.   

Abstract

Little data are available concerning conduit repair of digital nerve lesions. We are presenting a prospective two-center cohort study on digital nerve reconstruction with collagen nerve conduits. The data are put into the context of a comprehensive review of existing literature. Over a period of 3 years, all consecutive digital nerve lesions that could not be repaired by tensionless coaptation with a gap length of less than 26 mm were reconstructed with nerve conduits made from bovine collagen I. Sensibility was assessed 1 week, 3, 6, and 12 months postoperatively by static and moving 2-point-discrimination (2PD) and monofilament testing. Forty-nine digital nerve lesions in 40 patients met the inclusion criteria. The mean nerve gap was 12.3 ± 2.3 mm (span 5-25 mm). Forty nerve reconstructions could be included in the 12-month follow-up. Three cases, assessed 12 months postoperatively, showed excellent sensibility (static 2PD <6 mm). Seventeen achieved good (2PD 6-10 mm), 5 fair (2PD 11-15 mm), 6 poor (2PD >15 mm, but protective sensibility), and 9 achieved no sensibility. Monofilament test results were significantly better if gap length was shorter than 12 mm. Our results confirm tubulization as one possible technique in nerve reconstruction for gap lengths of 5 to 25 mm. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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Year:  2013        PMID: 24338485     DOI: 10.1055/s-0033-1358788

Source DB:  PubMed          Journal:  J Reconstr Microsurg        ISSN: 0743-684X            Impact factor:   2.873


  9 in total

1.  Sensory Outcomes in Digital Nerve Repair Techniques: An Updated Meta-analysis and Systematic Review.

Authors:  Zachary J Herman; Asif M Ilyas
Journal:  Hand (N Y)       Date:  2019-05-01

Review 2.  Nerve Repair with Nerve Conduits: Problems, Solutions, and Future Directions.

Authors:  Ryan Rebowe; Ashley Rogers; Xuebin Yang; S C Kundu; Thomas L Smith; Zhongyu Li
Journal:  J Hand Microsurg       Date:  2018-03-20

3.  Translational research in peripheral nerve repair and regeneration.

Authors:  Nektarios Sinis; Stefano Geuna; Fausto Viterbo
Journal:  Biomed Res Int       Date:  2014-09-09       Impact factor: 3.411

4.  An Optimized Collagen-Fibrin Blend Engineered Neural Tissue Promotes Peripheral Nerve Repair.

Authors:  Christina M A P Schuh; Adam G E Day; Heinz Redl; James Phillips
Journal:  Tissue Eng Part A       Date:  2018-06-13       Impact factor: 3.845

5.  Anatomical Considerations to Optimize Sensory Recovery in Breast Neurotization with Allograft.

Authors:  Ivica Ducic; Joshua Yoon; Arash Momeni; Uros Ahcan
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-11-07

Review 6.  Modification of tubular chitosan-based peripheral nerve implants: applications for simple or more complex approaches.

Authors:  Nina Dietzmeyer; Maria Förthmann; Claudia Grothe; Kirsten Haastert-Talini
Journal:  Neural Regen Res       Date:  2020-08       Impact factor: 5.135

7.  Nerve wrap after end-to-end and tension-free neurorrhaphy attenuates neuropathic pain: A prospective study based on cohorts of digit replantation.

Authors:  Xiaozhong Zhu; Haifeng Wei; Hongyi Zhu
Journal:  Sci Rep       Date:  2018-01-12       Impact factor: 4.379

Review 8.  Stem cell therapy for nerve injury.

Authors:  Sara Sayad Fathi; Arash Zaminy
Journal:  World J Stem Cells       Date:  2017-09-26       Impact factor: 5.326

9.  Long-term sensibility outcomes of secondary digital nerve reconstruction with sural nerve autografts: a retrospective study.

Authors:  Tomasz Dębski; Marcin Złotorowicz; Bartłomiej Henryk Noszczyk
Journal:  Eur J Trauma Emerg Surg       Date:  2021-07-19       Impact factor: 2.374

  9 in total

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