Literature DB >> 24337838

Aberrant DNA methylation in human cancers.

Wen Li1, Bi-Feng Chen2.   

Abstract

DNA methylation, one of the best-characterized epigenetic modifications, plays essential roles in diseases, including human cancers. In recent years, our understanding on DNA methylation with human cancers has made significant progress, which was facilitated by stunning development in the analysis of the human methylome of multiple cancer types. In this review, recent developments in the characterization of aberrant DNA methylation involved in human cancers development were discussed with special emphasis on the mechanisms of aberrant DNA methylation in human cancers. We also summarize the recent treatment strategy for human cancers with de-methylation drugs.

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Year:  2013        PMID： 24337838     DOI： 10.1007/s11596-013-1201-0

Source DB:  PubMed          Journal:  J Huazhong Univ Sci Technolog Med Sci        ISSN： 1672-0733


  68 in total

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Review 5.  Aberrant DNA methylation as a cancer-inducing mechanism.

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Journal:  Annu Rev Pharmacol Toxicol       Date:  2005       Impact factor: 13.820

Review 6.  DNA methylation, chromatin inheritance, and cancer.

Authors:  M R Rountree; K E Bachman; J G Herman; S B Baylin
Journal:  Oncogene       Date:  2001-05-28       Impact factor: 9.867

7.  The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation.

Authors:  Jing Wang; Sarah Hevi; Julia K Kurash; Hong Lei; Frédérique Gay; Jeffrey Bajko; Hui Su; Weitao Sun; Hua Chang; Guoliang Xu; François Gaudet; En Li; Taiping Chen
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8.  Cellular differentiation, cytidine analogs and DNA methylation.

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9.  PKC isoforms interact with and phosphorylate DNMT1.

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10.  Talking to chromatin: post-translational modulation of polycomb group function.

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Journal:  Epigenetics Chromatin       Date:  2009-09-01       Impact factor: 4.954
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  6 in total

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2.  Relationship between DLEC1 and PBX3 promoter methylation and the risk and prognosis of gastric cancer in peripheral blood leukocytes.

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3.  Co-Targeting Plk1 and DNMT3a in Advanced Prostate Cancer.

Authors:  Zhuangzhuang Zhang; Lijun Cheng; Qiongsi Zhang; Yifan Kong; Daheng He; Kunyu Li; Matthew Rea; Jianling Wang; Ruixin Wang; Jinghui Liu; Zhiguo Li; Chongli Yuan; Enze Liu; Yvonne N Fondufe-Mittendorf; Lang Li; Tao Han; Chi Wang; Xiaoqi Liu
Journal:  Adv Sci (Weinh)       Date:  2021-05-29       Impact factor: 17.521

4.  A miR-199a/miR-214 self-regulatory network via PSMD10, TP53 and DNMT1 in testicular germ cell tumor.

Authors:  Bi-Feng Chen; Yick-Keung Suen; Shen Gu; Lu Li; Wai-Yee Chan
Journal:  Sci Rep       Date:  2014-09-18       Impact factor: 4.379

5.  The DNMT3B -579G>T Polymorphism Is Significantly Associated With the Risk of Gastric Cancer but not Lung Cancer in Chinese Population.

Authors:  Bifeng Chen; Jingdong Wang; Xiuli Gu; Jingli Zhang; Jiankun Zhang; Xianhong Feng
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6.  Serum cell-free DNA methylation of OPCML and HOXD9 as a biomarker that may aid in differential diagnosis between cholangiocarcinoma and other biliary diseases.

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Journal:  Clin Epigenetics       Date:  2019-03-04       Impact factor: 6.551
  6 in total

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