Literature DB >> 24336894

Epidural analgesia in laparoscopic colorectal surgery: a nationwide analysis of use and outcomes.

Wissam J Halabi1, Celeste Y Kang1, Vinh Q Nguyen2, Joseph C Carmichael1, Steven Mills1, Michael J Stamos1, Alessio Pigazzi1.   

Abstract

IMPORTANCE: The use of epidural analgesia in laparoscopic colorectal surgery has demonstrated superiority over conventional analgesia in controlling pain. Controversy exists, however, regarding its cost-effectiveness and its effect on postoperative outcomes.
OBJECTIVES: To examine the use of epidural analgesia in laparoscopic colorectal surgery at the national level and to compare its outcomes with those of conventional analgesia. DESIGN, SETTING, AND PARTICIPANTS: This is a retrospective review of laparoscopic colorectal cases performed with or without epidural analgesia for cancer, diverticular disease, and benign polyps. Patient demographic characteristics, disease and procedure types, and hospital settings were listed for patients in the epidural and conventional analgesia groups. A 1 to 4 case-matched analysis was performed, matching for patient demographic characteristics, hospital setting, indications, and procedure type. Data were obtained from the Nationwide Inpatient Sample between January 1, 2002, and December 31, 2010. MAIN OUTCOMES AND MEASURES: Total hospital charge, length of stay, mortality, pneumonia, respiratory failure, urinary tract infection, urinary retention, anastomotic leak, and postoperative ileus.
RESULTS: A total of 191576 laparoscopic colorectal cases were identified during the study period. Epidural analgesia was used in 4102 cases (2.14%). Epidurals were more likely to be used in large teaching hospitals, cancer cases, and rectal operations. On case-matched analysis, epidural analgesia was associated with a longer hospital stay by 0.60 day (P=.003), higher hospital charges by $3732.71 (P=.02), and higher rate of urinary tract infection (odds ratio=1.81; P=.05). Epidural analgesia did not affect the incidence of respiratory failure, pneumonia, anastomotic leak, ileus, or urinary retention. CONCLUSIONS AND RELEVANCE: The perioperative use of epidural analgesia in laparoscopic colorectal surgery is limited in the United States. While epidural analgesia appears to be safe, it comes with higher hospital charges, longer hospital stay, and a higher incidence of urinary tract infections.

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Year:  2014        PMID: 24336894     DOI: 10.1001/jamasurg.2013.3186

Source DB:  PubMed          Journal:  JAMA Surg        ISSN: 2168-6254            Impact factor:   14.766


  36 in total

1.  Risk factors for postoperative ileus following elective laparoscopic right colectomy: a retrospective multicentric study.

Authors:  Lise Courtot; Bertrand Le Roy; Ricardo Memeo; Thibault Voron; Nicolas de Angelis; Nicolas Tabchouri; Francesco Brunetti; Anne Berger; Didier Mutter; Johan Gagniere; Ephrem Salamé; Denis Pezet; Mehdi Ouaïssi
Journal:  Int J Colorectal Dis       Date:  2018-05-07       Impact factor: 2.571

2.  Improved peri-operative outcomes with epidural analgesia in patients undergoing a pancreatectomy: a nationwide analysis.

Authors:  Dominic E Sanford; William G Hawkins; Ryan C Fields
Journal:  HPB (Oxford)       Date:  2015-02-28       Impact factor: 3.647

Review 3.  Postoperative Ileus.

Authors:  Cristina R Harnsberger; Justin A Maykel; Karim Alavi
Journal:  Clin Colon Rectal Surg       Date:  2019-04-02

4.  Clinical practice guideline for enhanced recovery after colon and rectal surgery from the American Society of Colon and Rectal Surgeons (ASCRS) and Society of American Gastrointestinal and Endoscopic Surgeons (SAGES).

Authors:  Joseph C Carmichael; Deborah S Keller; Gabriele Baldini; Liliana Bordeianou; Eric Weiss; Lawrence Lee; Marylise Boutros; James McClane; Scott R Steele; Liane S Feldman
Journal:  Surg Endosc       Date:  2017-08-03       Impact factor: 4.584

Review 5.  Pain Management in Enhanced Recovery after Surgery (ERAS) Protocols.

Authors:  J Creswell Simpson; Xiaodong Bao; Aalok Agarwala
Journal:  Clin Colon Rectal Surg       Date:  2019-02-28

Review 6.  Reducing the burden of postoperative ileus: evaluating and implementing an evidence-based strategy.

Authors:  Jeffrey F Barletta; Anthony J Senagore
Journal:  World J Surg       Date:  2014-08       Impact factor: 3.352

7.  The 2014 Jagelman/Turnbull International Colorectal Disease Symposium, Ft Lauderdale (FL).

Authors:  I Montroni; N Haim
Journal:  Tech Coloproctol       Date:  2014-07       Impact factor: 3.781

8.  Epidural analgesia in the era of enhanced recovery: time to rethink its use?

Authors:  Ahmed M Al-Mazrou; James M Kiely; Ravi P Kiran
Journal:  Surg Endosc       Date:  2018-10-23       Impact factor: 4.584

Review 9.  Pain management in abdominal surgery.

Authors:  Thomas M Hemmerling
Journal:  Langenbecks Arch Surg       Date:  2018-10-03       Impact factor: 3.445

10.  Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection.

Authors:  Tadashi Yoshida; Shigenori Homma; Susumu Shibasaki; Tatsushi Shimokuni; Hideyasu Sakihama; Norihiko Takahashi; Hideki Kawamura; Akinobu Taketomi
Journal:  Surg Today       Date:  2016-05-19       Impact factor: 2.549

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