Recurrent multifocal choroiditis.

The authors examined 11 young adult, moderately myopic female patients who presented with visual loss secondary to a newly described disorder consisting of multiple small discrete lesions at the level of the retinal pigment epithelium and choriocapillaris. The condition appears to be inflammatory and occurs primarily in the macula and posterior pole. Disc edema and a mild vitritis may be present. The condition was bilateral in five patients, although the fellow eye was asymptomatic in each case. Multiple recurrences are common, with new sites developing adjacent to old ones. Four of the 11 patients had subretinal neovascularization develop from parafoveal lesions. The inflammatory lesions, as well as the subretinal neovascularization, regressed with corticosteroid treatment, and most patients recovered excellent visual acuity. Systemic laboratory studies were noncontributory.