Literature DB >> 24336227

Pairwise Sequence Alignment for Very Long Sequences on GPUs.

Junjie Li1, Sanjay Ranka, Sartaj Sahni.   

Abstract

We develop novel single-GPU parallelizations of the Smith-Waterman algorithm for pairwise sequence alignment. Our algorithms, which are suitable for the alignment of a single pair of very long sequences, can be used to determine the alignment score as well as the actual alignment. Experimental results demonstrate an order of magnitude reduction in run time relative to competing GPU algorithms.

Entities:  

Keywords:  CUDA; GPU; Long sequence alignment; Smith-Waterman algorithm; local alignment

Year:  2012        PMID: 24336227      PMCID: PMC3855353          DOI: 10.1109/ICCABS.2012.6182641

Source DB:  PubMed          Journal:  IEEE Int Conf Comput Adv Bio Med Sci        ISSN: 2164-229X


  8 in total

1.  Basic local alignment search tool.

Authors:  S F Altschul; W Gish; W Miller; E W Myers; D J Lipman
Journal:  J Mol Biol       Date:  1990-10-05       Impact factor: 5.469

2.  Rapid and sensitive protein similarity searches.

Authors:  D J Lipman; W R Pearson
Journal:  Science       Date:  1985-03-22       Impact factor: 47.728

3.  A general method applicable to the search for similarities in the amino acid sequence of two proteins.

Authors:  S B Needleman; C D Wunsch
Journal:  J Mol Biol       Date:  1970-03       Impact factor: 5.469

4.  A local alignment tool for very long DNA sequences.

Authors:  K M Chao; J Zhang; J Ostell; W Miller
Journal:  Comput Appl Biosci       Date:  1995-04

5.  Identification of common molecular subsequences.

Authors:  T F Smith; M S Waterman
Journal:  J Mol Biol       Date:  1981-03-25       Impact factor: 5.469

6.  An improved algorithm for matching biological sequences.

Authors:  O Gotoh
Journal:  J Mol Biol       Date:  1982-12-15       Impact factor: 5.469

7.  CUDASW++2.0: enhanced Smith-Waterman protein database search on CUDA-enabled GPUs based on SIMT and virtualized SIMD abstractions.

Authors:  Yongchao Liu; Bertil Schmidt; Douglas L Maskell
Journal:  BMC Res Notes       Date:  2010-04-06

8.  CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment.

Authors:  Svetlin A Manavski; Giorgio Valle
Journal:  BMC Bioinformatics       Date:  2008-03-26       Impact factor: 3.169

  8 in total

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