Literature DB >> 24334968

First case of 18F-FACBC PET/CT-guided salvage retroperitoneal lymph node dissection for disease relapse after radical prostatectomy for prostate cancer and negative 11C-choline PET/CT: new imaging techniques may expand pioneering approaches.

Riccardo Schiavina1, Sergio Concetti, Eugenio Brunocilla, Cristina Nanni, Marco Borghesi, Giorgio Gentile, Matteo Cevenini, Lorenzo Bianchi, Enrico Molinaroli, Stefano Fanti, Giuseppe Martorana.   

Abstract

We present the first case of salvage retroperitoneal lymph node dissection based on the results of (18)F-FACBC PET/CT performed for a prostate-specific antigen relapse after radical prostatectomy. The patients underwent (11)C-choline PET/CT, which turned out negative, while (18)F-FACBC PET/CT visualized two lymph node metastases confirmed at pathological examination. Preliminary clinical reports showed an improvement in the detection rate of 20-40% for (18)F-FACBC in comparison with (11)C-choline, rendering the (18)F-FACBC the potential radiotracer of the future. Salvage surgery for prostate cancer is a fascinating but controversial approach. New diagnostic tools may improve its potential by increasing the assessment and the selection of the patients. 2013 S. Karger AG, Basel.

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Year:  2013        PMID： 24334968     DOI： 10.1159/000354730

Source DB:  PubMed          Journal:  Urol Int        ISSN： 0042-1138            Impact factor:   2.089


  8 in total

1.  18F-Fluciclovine PET metabolic imaging reveals prostate cancer tumour heterogeneity associated with disease resistance to androgen deprivation therapy.

Authors:  Gaurav Malviya; Rachana Patel; Mark Salji; Rafael S Martinez; Peter Repiscak; Ernest Mui; Susan Champion; Agata Mrowinska; Emma Johnson; Maha AlRasheedi; Sally Pimlott; David Lewis; Hing Y Leung
Journal:  EJNMMI Res       Date:  2020-11-25       Impact factor: 3.138

Review 2.  PET imaging for lymph node dissection in prostate cancer.

Authors:  Elena Incerti; Paola Mapelli; Luigi Gianolli; Maria Picchio
Journal:  World J Urol       Date:  2016-10-17       Impact factor: 4.226

Review 3.  [Salvage lymphadenectomy in patients with prostate cancer recurrence: A review].

Authors:  D K Osmonov; A V Aksenov; C A Jilg; W Schultze-Seeman; C M Naumann; M F Hamann; K Bothe; K-P Jünemann
Journal:  Urologe A       Date:  2016-02       Impact factor: 0.639

Review 4.  [Molecular multimodal hybrid imaging in prostate and bladder cancer].

Authors:  T Maurer; M Eiber; B J Krause
Journal:  Urologe A       Date:  2014-04       Impact factor: 0.639

5.  [18F]Fluciclovine-PET Guided Salvage Lymph Node Dissection Following Radical Prostatectomy.

Authors:  Samuel J Galgano; Carli E Calderone; Jeffrey W Nix; Soroush Rais-Bahrami
Journal:  Urology       Date:  2019-05-29       Impact factor: 2.649

Review 6.  Fluorine-18 labeled amino acids for tumor PET/CT imaging.

Authors:  Yiqiang Qi; Xiaohui Liu; Jun Li; Huiqian Yao; Shuanghu Yuan
Journal:  Oncotarget       Date:  2017-08-04

Review 7.  Fluciclovine positron emission tomography in the setting of biochemical recurrence following local therapy of prostate cancer.

Authors:  Zachary A Glaser; Soroush Rais-Bahrami
Journal:  Transl Androl Urol       Date:  2018-10

8.  The Role of [18F]Fluciclovine PET/CT in the Characterization of High-Risk Primary Prostate Cancer: Comparison with [11C]Choline PET/CT and Histopathological Analysis.

Authors:  Lucia Zanoni; Riccardo Mei; Lorenzo Bianchi; Francesca Giunchi; Lorenzo Maltoni; Cristian Vincenzo Pultrone; Cristina Nanni; Irene Bossert; Antonella Matti; Riccardo Schiavina; Michelangelo Fiorentino; Cristina Fonti; Filippo Lodi; Antonietta D'Errico; Eugenio Brunocilla; Stefano Fanti
Journal:  Cancers (Basel)       Date:  2021-03-29       Impact factor: 6.639
  8 in total

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