Ayako Imaizumi1, Shunji Kusaka2, Hiroe Noguchi3, Yoshikazu Shimomura4, Shoichi Sawaguchi5. 1. Department of Ophthalmology, Naha City Hospital, Okinawa, Japan; Department of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan. 2. Department of Ophthalmology, Sakai Hospital Kinki University Faculty of Medicine, Osaka, Japan. Electronic address: kusaka-ns@umin.net. 3. Department of Ophthalmology, Naha City Hospital, Okinawa, Japan. 4. Department of Ophthalmology, Sakai Hospital Kinki University Faculty of Medicine, Osaka, Japan. 5. Department of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Abstract
PURPOSE: To evaluate the efficacy of perfluoro-n-octane as a postoperative short-term tamponade after vitrectomy in pediatric cases with complex retinal detachment (RD) and proliferative vitreoretinopathy (PVR). DESIGN: Prospective, noncomparative, interventional case series. METHODS: The medical records of 10 eyes of 9 children (6 boys and 3 girls), whose age ranged from 3 months to 11 years, with a median of 7.5 months, were reviewed. The cause of the PVR was retinopathy of prematurity (7 eyes of 6 patients); familial exudative vitreoretinopathy; or tractional RD associated with congenital optic nerve anomalies,(1) and persistent fetal vasculature. Perfluoro-n-octane was injected into the eyes at the primary surgery in 2 eyes and at the repeat surgeries in 8 eyes. The perfluoro-n-octane was removed after 1 to 4 postoperative weeks. The patients were followed for 5 to 43 months. RESULTS: At the last examination, the retinas were reattached in 8 eyes (80%). In the other two eyes, a retinal attachment was not obtained. Postoperatively, the best-corrected visual acuity improved from hand motion to 0.1 in 1 eye and could not be measured in the other 9 patients because of their ages. No apparent adverse events related to the use of perfluoro-n-octane were noted. CONCLUSIONS: Although cautions should be exercised regarding potential mechanical retinal injuries by heavy liquids in the eye, short-term perfluoro-n-octane tamponade was effective in pediatric cases with severe PVR in which retinal reattachment is considered to be difficult with conventional gas or silicone oil tamponade.
PURPOSE: To evaluate the efficacy of perfluoro-n-octane as a postoperative short-term tamponade after vitrectomy in pediatric cases with complex retinal detachment (RD) and proliferative vitreoretinopathy (PVR). DESIGN: Prospective, noncomparative, interventional case series. METHODS: The medical records of 10 eyes of 9 children (6 boys and 3 girls), whose age ranged from 3 months to 11 years, with a median of 7.5 months, were reviewed. The cause of the PVR was retinopathy of prematurity (7 eyes of 6 patients); familial exudative vitreoretinopathy; or tractional RD associated with congenital optic nerve anomalies,(1) and persistent fetal vasculature. Perfluoro-n-octane was injected into the eyes at the primary surgery in 2 eyes and at the repeat surgeries in 8 eyes. The perfluoro-n-octane was removed after 1 to 4 postoperative weeks. The patients were followed for 5 to 43 months. RESULTS: At the last examination, the retinas were reattached in 8 eyes (80%). In the other two eyes, a retinal attachment was not obtained. Postoperatively, the best-corrected visual acuity improved from hand motion to 0.1 in 1 eye and could not be measured in the other 9 patients because of their ages. No apparent adverse events related to the use of perfluoro-n-octane were noted. CONCLUSIONS: Although cautions should be exercised regarding potential mechanical retinal injuries by heavy liquids in the eye, short-term perfluoro-n-octane tamponade was effective in pediatric cases with severe PVR in which retinal reattachment is considered to be difficult with conventional gas or silicone oil tamponade.
Authors: Naresh Babu; Piyush Kohli; Karthik Kumar; Renu P Rajan; Girish Baliga; Sagnik Sen; N O Ramachandran; S Bhavani; Kim Ramasamy Journal: Int Ophthalmol Date: 2020-08-28 Impact factor: 2.031