OBJECTIVE: To evaluate clinical oral and salivary parameters of individuals with juvenile idiopathic arthritis (JIA). STUDY DESIGN: Clinical parameters and whole saliva were collected from children aged 6 to 12 years with JIA (n = 36) and from a healthy, matched control group (n = 36). The clinical and salivary parameters evaluated were the dental caries (decayed, missing, or filled teeth), gingival and simplified oral hygiene indices, salivary flow rate, pH, buffer capacity, total protein, and secretory immunoglobulin A concentrations. RESULTS: JIA individuals presented poorer oral hygiene (P ≤ .05) but no difference in the dental caries and gingival indices. JIA patients presented an increase in total protein concentration (86%) and buffer capacity in the range of pH 6.9 to 6.0 (10%) and a reduction in initial pH (6%), buffer capacity in the range of pH ≥ 7.0 (50%), and immunoglobulin A concentration (27%) (P ≤ .05). CONCLUSIONS: JIA is associated with poor oral hygiene and salivary changes, including reductions in immune factors and an altered profile of salivary buffer capacity.
OBJECTIVE: To evaluate clinical oral and salivary parameters of individuals with juvenile idiopathic arthritis (JIA). STUDY DESIGN: Clinical parameters and whole saliva were collected from children aged 6 to 12 years with JIA (n = 36) and from a healthy, matched control group (n = 36). The clinical and salivary parameters evaluated were the dental caries (decayed, missing, or filled teeth), gingival and simplified oral hygiene indices, salivary flow rate, pH, buffer capacity, total protein, and secretory immunoglobulin A concentrations. RESULTS: JIA individuals presented poorer oral hygiene (P ≤ .05) but no difference in the dental caries and gingival indices. JIA patients presented an increase in total protein concentration (86%) and buffer capacity in the range of pH 6.9 to 6.0 (10%) and a reduction in initial pH (6%), buffer capacity in the range of pH ≥ 7.0 (50%), and immunoglobulin A concentration (27%) (P ≤ .05). CONCLUSIONS: JIA is associated with poor oral hygiene and salivary changes, including reductions in immune factors and an altered profile of salivary buffer capacity.
Authors: Marit S Skeie; Elisabeth G Gil; Lena Cetrelli; Annika Rosén; Johannes Fischer; Anne Nordrehaug Åstrøm; Keijo Luukko; Xieqi Shi; Astrid J Feuerherm; Abhijit Sen; Paula Frid; Marite Rygg; Athanasia Bletsa Journal: BMC Oral Health Date: 2019-12-19 Impact factor: 2.757
Authors: Paula Frid; Divyashri Baraniya; Josefine Halbig; Veronika Rypdal; Nils Thomas Songstad; Annika Rosèn; Johanna Rykke Berstad; Berit Flatø; Fadhl Alakwaa; Elisabeth Grut Gil; Lena Cetrelli; Tsute Chen; Nezar Noor Al-Hebshi; Ellen Nordal; Mohammed Al-Haroni Journal: Front Cell Infect Microbiol Date: 2020-11-04 Impact factor: 5.293
Authors: Lena Cetrelli; Athanasia Bletsa; Anette Lundestad; Elisabet Grut Gil; Johannes Fischer; Josefine Halbig; Paula Frid; Oskar Angenete; Ingrid Lillevoll; Annika Rosén; Karin B Tylleskär; Keio Luukko; Ellen Nordal; Anne Nordrehaug Åstrøm; Marit Slåttelid Skeie; Astrid Jullumstrø Feuerherm; Abhijit Sen; Marite Rygg Journal: BMC Oral Health Date: 2022-08-08 Impact factor: 3.747