OBJECTIVE: The aim of our study is to elucidate the association between leptin and obesity in Mongolian women. METHOD: Total 181 women participated in the study including 118 Mongolians and 63 Han. Body mass index (BMI) was calculated by weight (kg) divided by square height (m²). Percent body fat (%fat) was detected by bioelectrical impedance analysis (BIA). Fasting serum leptin was determined by ELISA. RESULT: The average BMI and %fat of Mongolian and Han women was 25.14 ± 4.48 kg/m², 24.30 ± 3.62 kg/m² and 36.10 ± 6.23%, 33.84 ± 5.98%, respectively. Fasting serum leptin level in obese women (BMI ≥ 25) was remarkably higher than in normal weight women (18.5 < BMI < 25) in Mongolian and Han ethnic groups (all P < 0.001). Fasting serum leptin level in Mongolian women had borderline significance compared with it in Han women (P = 0.049). Multiple linear regression models revealed that ethnicity, %fat and BMI were associated with serum leptin concentrations independent of age. CONCLUSION: In Mongolian and Han women, fasting serum leptin level was positively associated with BMI and %fat (all P < 0.001).
OBJECTIVE: The aim of our study is to elucidate the association between leptin and obesity in Mongolian women. METHOD: Total 181 women participated in the study including 118 Mongolians and 63 Han. Body mass index (BMI) was calculated by weight (kg) divided by square height (m²). Percent body fat (%fat) was detected by bioelectrical impedance analysis (BIA). Fasting serum leptin was determined by ELISA. RESULT: The average BMI and %fat of Mongolian and Han women was 25.14 ± 4.48 kg/m², 24.30 ± 3.62 kg/m² and 36.10 ± 6.23%, 33.84 ± 5.98%, respectively. Fasting serum leptin level in obesewomen (BMI ≥ 25) was remarkably higher than in normal weight women (18.5 < BMI < 25) in Mongolian and Han ethnic groups (all P < 0.001). Fasting serum leptin level in Mongolian women had borderline significance compared with it in Han women (P = 0.049). Multiple linear regression models revealed that ethnicity, %fat and BMI were associated with serum leptin concentrations independent of age. CONCLUSION: In Mongolian and Han women, fasting serum leptin level was positively associated with BMI and %fat (all P < 0.001).
Authors: Sara García-Jiménez; German Bernal Fernández; Maria Fernanda Martínez Salazar; Antonio Monroy Noyola; Cairo Toledano Jaimes; Angelica Meneses Acosta; Leticia Gonzalez Maya; Elizabeth Aveleyra Ojeda; Maria A Terrazas Meraz; Marie-Catherine Boll; Miguel A Sánchez-Alemán Journal: J Clin Lab Anal Date: 2014-03-22 Impact factor: 2.352
Authors: Alena A Nikanorova; Nikolay A Barashkov; Vera G Pshennikova; Sergey S Nakhodkin; Nyurgun N Gotovtsev; Georgii P Romanov; Aisen V Solovyev; Sargylana S Kuzmina; Nikolay N Sazonov; Sardana A Fedorova Journal: Int J Mol Sci Date: 2021-04-28 Impact factor: 5.923
Authors: Anna Lubkowska; Aleksandra Radecka; Iwona Bryczkowska; Iwona Rotter; Maria Laszczyńska; Wioleta Dudzińska Journal: Int J Environ Res Public Health Date: 2015-09-14 Impact factor: 3.390