Lin-Huang Huang1, Ying-Li Liao2, Chung-Hua Hsu3. 1. Committee on Chinese Medicine and Pharmacy, Department of Health, Executive Yuan, Taiwan. 2. Department of Endocrinology, Taipei Hospital, Taiwan. 3. Branch of Lin-Sen and Chinese Medicine, Taipei City Hospital, Taipei, Taiwan. Electronic address:owlherbs@yahoo.com.tw.
Abstract
UNLABELLED: Summay: BACKGROUND: Insulin resistance is an important pathogenic factor in type 2 diabetes patents. An easy and efficiency measurement predicting insulin resistance; which can be done easily by type 2 patients is desired. OBJECTIVE: To examine whether waist circumference is a better predictor of insulin resistance in type 2 diabetes than body mass index (BMI). METHODS: From a population of 1356 registered diabetic patients, 144 who met (1) aged between 30 and 75 years, (2) being Chinese, (3) having had type 2 diabetes for more than one year, and (4) having been taking gliclazide and metformin for more than 6 months were enrolled in this study. The main outcome evaluated is the associations of HOMA insulin resistance index (HOMA index); which were assessed using multiple linear regression analysis. RESULTS: The coefficients of multiple regression analysis with stepwise model showed that waist circumference (β = 0.35, p < 0.001) but not BMI (β = 0.01, p = 0.94), adiponectin (β = -0.25, p = 0.04) and hemoglobulin A1c% (HbA1c) (β = 0.25, p = 0.01) were the main predictors of HOMA index. CONCLUSIONS: These initial findings indicate that waist circumference is a better predictor of insulin resistance in type 2 diabetes than BMI. Â
UNLABELLED: Summay: BACKGROUND:Insulin resistance is an important pathogenic factor in type 2 diabetes patents. An easy and efficiency measurement predicting insulin resistance; which can be done easily by type 2 patients is desired. OBJECTIVE: To examine whether waist circumference is a better predictor of insulin resistance in type 2 diabetes than body mass index (BMI). METHODS: From a population of 1356 registered diabeticpatients, 144 who met (1) aged between 30 and 75 years, (2) being Chinese, (3) having had type 2 diabetes for more than one year, and (4) having been taking gliclazide and metformin for more than 6 months were enrolled in this study. The main outcome evaluated is the associations of HOMA insulin resistance index (HOMA index); which were assessed using multiple linear regression analysis. RESULTS: The coefficients of multiple regression analysis with stepwise model showed that waist circumference (β = 0.35, p < 0.001) but not BMI (β = 0.01, p = 0.94), adiponectin (β = -0.25, p = 0.04) and hemoglobulin A1c% (HbA1c) (β = 0.25, p = 0.01) were the main predictors of HOMA index. CONCLUSIONS: These initial findings indicate that waist circumference is a better predictor of insulin resistance in type 2 diabetes than BMI. Â
Authors: Wai Fong Chew; Pooi Pooi Leong; Sook Fan Yap; A Malik Yasmin; Kong Bung Choo; Gary Kim Kuan Low; Nem Yun Boo Journal: Singapore Med J Date: 2017-02-17 Impact factor: 1.858
Authors: Chandra Yogal; Sunila Shakya; Biraj Karmarcharya; Rajendra Koju; Astrid Kamilla Stunes; Mats Peder Mosti; Miriam K Gustafsson; Bjørn Olav Åsvold; Berit Schei; Unni Syversen Journal: Int J Environ Res Public Health Date: 2022-06-08 Impact factor: 4.614
Authors: Wambui G Gathirua-Mwangi; Patrick Monahan; Yiqing Song; Terrell W Zollinger; Victoria L Champion; Timothy E Stump; Thomas F Imperiale Journal: Dig Dis Sci Date: 2017-10-05 Impact factor: 3.199
Authors: Sara Gustavsson; Björn Fagerberg; Gerd Sallsten; Eva M Andersson Journal: Int J Environ Res Public Health Date: 2014-03-27 Impact factor: 3.390
Authors: Anita Lukács; Edina Horváth; Zsuzsanna Máté; Andrea Szabó; Katalin Virág; Magor Papp; János Sándor; Róza Ádány; Edit Paulik Journal: BMC Public Health Date: 2019-11-15 Impact factor: 3.295