Literature DB >> 24327454

Evaluating clinical course of BCG lymphadenitis and factors affect on it during a 5-year period in Kerman, Iran.

Mohammadhossein Daei Parizi1, Amirhossein Kardoust Parizi, Sepide Izadipour.   

Abstract

INTRODUCTION: One of the preventive methods of pulmonary tuberculosis is bacillus Calmette-Guérin (BCG) vaccination and one of the common complications of vaccine is lymphadenitis. We aimed to evaluate clinical course of BCG lymphadenitis in children of Kerman Province, Iran.
METHOD: 314 children with BCG lymphadenitis were enrolled in study. Patients were followed up monthly regarding clinical improvement and complications.
RESULTS: BCG lymphadenitis was improved in many patients during follow up; during 6 months 23.7% of patients had spontaneous regression. Only the primary size of lymphadenitis had significant effect on clinical course of lymphadenitis and developing complication (p = 0.0540).
CONCLUSION: Many patients improved without any intervention. The primary size of lymphadenitis may affect clinical course of lymphadenitis and dispose person to abscess and fistula. To confirm this result and evaluate efficiency of preventive surgery instead of observation further study is recommended.

Entities:  

Keywords:  BCG lymphadenitis; BCG vaccination; abscess; clinical course; fistula; spontaneous regression

Mesh:

Substances:

Year:  2013        PMID: 24327454     DOI: 10.1093/tropej/fmt100

Source DB:  PubMed          Journal:  J Trop Pediatr        ISSN: 0142-6338            Impact factor:   1.165


  5 in total

1.  BCG vaccination-induced suppurative lymphadenitis: four signs to pay attention to.

Authors:  Sang Oon Baek; Hyo Sun Ko; Hyun Ho Han
Journal:  Int Wound J       Date:  2017-04-19       Impact factor: 3.315

2.  Clinical Course of Bacillus Calmette-Guerin Lymphadenitis.

Authors:  Dayoung Ko; Ji-Won Han; Joongkee Youn; Hee-Beom Yang; Chaeyoun Oh; Ki-Wook Yun; Hyun-Young Kim
Journal:  Children (Basel)       Date:  2022-04-25

3.  Adverse reactions to Mycobacterium bovis bacille Calmette-Guérin vaccination against tuberculosis in Iranian children.

Authors:  Shima Mahmoudi; Saeid Khaheshi; Babak Pourakbari; Asghar Aghamohammadi; Sepideh Keshavarz Valian; Abbas Bahador; Farah Sabouni; Amitis Ramezani; Setareh Mamishi
Journal:  Clin Exp Vaccine Res       Date:  2015-07-29

Review 4.  The double-sided effects of Mycobacterium Bovis bacillus Calmette-Guérin vaccine.

Authors:  Junli Li; Lingjun Zhan; Chuan Qin
Journal:  NPJ Vaccines       Date:  2021-01-25       Impact factor: 7.344

5.  A study of the incidence of BCG vaccine complications in infants of Babol, Mazandaran (2011-2013).

Authors:  Rahim Barari-Savadkouhi; Azin Shour; Jila Masrour-Roudsari
Journal:  Caspian J Intern Med       Date:  2016
  5 in total

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