Literature DB >> 24325872

Molecular characteristics of MDR Mycobacterium tuberculosis strains isolated in Fujian, China.

Qiuyang Chen1, Yu Pang2, Qingfu Liang1, Shufang Lin1, Yufeng Wang2, Jian Lin1, Yong Zhao1, Shuzhen Wei1, Jinfeng Zheng3, Suhua Zheng4.   

Abstract

Of 75 MDR isolates from Fujian Province, the sensitivity of RIF, INH, EMB, SM, OFLX and KAN resistance by DNA sequencing was 96.0%, 96.0%, 66.7%, 66.0%, 84.2% and 75.0%, respectively. We also identified that minority mutations in the mixed Mycobacterium tuberculosis population may be responsible for two "false-negative" results. In addition, Beijing genotype is still the predominant sublineage in the MDR TB cases from Fujian.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  MDR; Molecular characteristics; Mycobacterium tuberculosis

Mesh：

Substances：

Year:  2013        PMID： 24325872     DOI： 10.1016/j.tube.2013.03.004

Source DB:  PubMed          Journal:  Tuberculosis (Edinb)        ISSN： 1472-9792            Impact factor:   3.131


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