Literature DB >> 24325266

A metal-free tandem C-C/C-O bond formation approach to diversely functionalized tetrasubstituted furans.

Chada Raji Reddy1, Motatipally Damoder Reddy.   

Abstract

A novel and efficient method for the synthesis of diversely functionalized furans is developed via DBU-mediated tandem Michael addition/5-exo-dig-cycloisomerization of enynes and keto-methylenes. This [3 + 2]-annulation is operationally simple under metal-free reaction conditions with 100% atom economy and broad substrate scope.

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Year:  2013        PMID: 24325266     DOI: 10.1021/jo4023342

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Synthesis and biological evaluation of (-)-kunstleramide and its derivatives.

Authors:  R Venkateshwarlu; B Chinnababu; U Ramulu; K Purushotham Reddy; M Damoder Reddy; P Sowjanya; P Venkateswara Rao; S Aravind
Journal:  Medchemcomm       Date:  2016-12-09       Impact factor: 3.597

2.  Unified Approach to Furan Natural Products via Phosphine-Palladium Catalysis.

Authors:  Violet Yijang Chen; Ohyun Kwon
Journal:  Angew Chem Int Ed Engl       Date:  2021-03-08       Impact factor: 15.336

  2 in total

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