Literature DB >> 24324101

Usefulness of 18F-fluorodeoxyglucose positron emission tomography as predictor of distant metastasis in preoperative carbon-ion radiotherapy for pancreatic cancer.

Makoto Shinoto1, Shigeru Yamada, Kyosan Yoshikawa, Shigeo Yasuda, Yoshiyuki Shioyama, Hiroshi Honda, Tadashi Kamada, Hirohiko Tsujii.   

Abstract

AIM: The purpose of this study was to evaluate the role of FDG-PET regarding the indication of preoperative carbon-ion radiotherapy (CIRT) for pancreatic cancer patients. PATIENTS AND METHODS: Patients with resectable pancreatic cancer underwent preoperative CIRT. The impact of baseline SUVmax on prognosis for patients was assessed by analyzing correlations with distant metastasis-free survival (DMFS) and overall survival (OS).
RESULTS: Out of 21 patients, local recurrence was observed in no patient and distant metastasis was found in 13 patients (62%). 1-year DMFS and OS in low-SUVmax group were significantly higher than those in high-SUVmax group (91% vs. 20% and 91% vs. 56%). SUVmax was significantly correlated with DMFS and OS.
CONCLUSION: Our data indicated a significant correlation between SUVmax and DMFS. FDG-PET might be useful for determining the indication of preoperative short-course CIRT for patients with resectable pancreatic cancer.

Entities:  

Keywords:  FDG-PET; carbon-ion radiotherapy; distant metastasis; preoperative; prognostic factor

Mesh:

Substances:

Year:  2013        PMID: 24324101

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  5 in total

Review 1.  Advancement in treatment and diagnosis of pancreatic cancer with radiopharmaceuticals.

Authors:  Yu-Ping Xu; Min Yang
Journal:  World J Gastrointest Oncol       Date:  2016-02-15

2.  Evaluation of 68Ga-labeled MG7 antibody: a targeted probe for PET/CT imaging of gastric cancer.

Authors:  Bing Xu; Xiaowei Li; Jipeng Yin; Cong Liang; Lijuan Liu; Zhaoyan Qiu; Liping Yao; Yongzhan Nie; Jing Wang; Kaichun Wu
Journal:  Sci Rep       Date:  2015-03-03       Impact factor: 4.379

3.  Prognostic Value of Metabolic and Volumetric Parameters of Preoperative FDG-PET/CT in Patients With Resectable Pancreatic Cancer.

Authors:  Hyung-Jun Im; Suthet Oo; Woohyun Jung; Jin-Young Jang; Sun-Whe Kim; Gi Jeong Cheon; Keon Wook Kang; June-Key Chung; E Edmund Kim; Dong Soo Lee
Journal:  Medicine (Baltimore)       Date:  2016-05       Impact factor: 1.889

Review 4.  Prognostic value of 18F-FDG-PET/CT parameters in patients with pancreatic carcinoma: A systematic review and meta-analysis.

Authors:  Dongyong Zhu; Lisha Wang; Hanfei Zhang; Jie Chen; Yanfang Wang; Sama Byanju; Meiyan Liao
Journal:  Medicine (Baltimore)       Date:  2017-08       Impact factor: 1.889

5.  Preoperative Metabolic Tumor Volume2.5 Associated with Early Systemic Metastasis in Resected Pancreatic Cancer: A Transcriptome-Wide Analysis.

Authors:  Sung Hwan Lee; Ho Kyoung Hwang; Woo Jung Lee; Mijin Yun; Chang Moo Kang
Journal:  Gut Liver       Date:  2019-05-15       Impact factor: 4.519

  5 in total

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