Literature DB >> 24320212

Genetic association between NOD2 polymorphism and infection status by Mycobacterium avium ssp. paratuberculosis in German Holstein cattle.

J D Küpper1, H R Brandt, G Erhardt.   

Abstract

The aim of the study was the analysis of the nucleotide-binding oligomerization domain containing 2 (NOD2, formerly CARD15) as a candidate gene for Mycobacterium avium ssp. paratuberculosis infection in cattle. Eleven SNPs in the NOD2 gene were identified, and finally, four SNPs were included in a case-control study using 324 German Holstein cows tested for paratuberculosis using fecal culture and ELISA. The SNP (GenBank) AY518738S04:g.521G>A in exon 4 showed a significant association between the fecal culture status of the animals and NOD2 allele variants. The other three SNPs showed no associations in German Holstein cows.
© 2013 Stichting International Foundation for Animal Genetics.

Entities:  

Keywords:  CARD15; bovine; candidate gene; fecal culture; nucleotide-binding oligomerization domain containing 2; paratuberculosis

Mesh：

Substances：

Year:  2013        PMID： 24320212     DOI： 10.1111/age.12097

Source DB:  PubMed          Journal:  Anim Genet        ISSN： 0268-9146            Impact factor:   3.169


  7 in total

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Journal:  Trop Anim Health Prod       Date:  2017-05-19       Impact factor: 1.559

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Journal:  PLoS One       Date:  2021-08-27       Impact factor: 3.240

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Journal:  Front Vet Sci       Date:  2021-02-12

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5.  CARD15 Gene Polymorphisms Are Associated with Tuberculosis Susceptibility in Chinese Holstein Cows.

Authors:  Youtao Wang; Shengkui Wang; Tong Liu; Wenji Tu; Wengui Li; Guodong Dong; Cong Xu; Bo Qin; Kaihua Liu; Jie Yang; Jun Chai; Xianwei Shi; Yifang Zhang
Journal:  PLoS One       Date:  2015-08-05       Impact factor: 3.240

6.  Genetic association analysis of paratuberculosis forms in holstein-friesian cattle.

Authors:  Patricia Vázquez; Otsanda Ruiz-Larrañaga; Joseba M Garrido; Mikel Iriondo; Carmen Manzano; Mikel Agirre; Andone Estonba; Ramón A Juste
Journal:  Vet Med Int       Date:  2014-05-20

7.  Association between combinations of genetic polymorphisms and epidemiopathogenic forms of bovine paratuberculosis.

Authors:  Ramon A Juste; Patricia Vazquez; Otsanda Ruiz-Larrañaga; Mikel Iriondo; Carmen Manzano; Mikel Agirre; Andone Estonba; Maria V Geijo; Elena Molina; Iker A Sevilla; Marta Alonso-Hearn; Nieves Gomez; Valentin Perez; Adoracion Cortes; Joseba M Garrido
Journal:  Heliyon       Date:  2018-03-01
  7 in total

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