Literature DB >> 24319093

2-Hydroxyglutarate is not a metabolite; D-2-hydroxyglutarate and L-2-hydroxyglutarate are!

Eduard A Struys1.   

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Year:  2013        PMID： 24319093      PMCID： PMC3870664          DOI： 10.1073/pnas.1318777110

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  3 in total

1.  Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Authors:  Lenny Dang; David W White; Stefan Gross; Bryson D Bennett; Mark A Bittinger; Edward M Driggers; Valeria R Fantin; Hyun Gyung Jang; Shengfang Jin; Marie C Keenan; Kevin M Marks; Robert M Prins; Patrick S Ward; Katharine E Yen; Linda M Liau; Joshua D Rabinowitz; Lewis C Cantley; Craig B Thompson; Matthew G Vander Heiden; Shinsan M Su
Journal:  Nature       Date:  2009-12-10       Impact factor: 49.962

2.  Measurement of urinary D- and L-2-hydroxyglutarate enantiomers by stable-isotope-dilution liquid chromatography-tandem mass spectrometry after derivatization with diacetyl-L-tartaric anhydride.

Authors:  Eduard A Struys; Erwin E W Jansen; Nanda M Verhoeven; Cornelis Jakobs
Journal:  Clin Chem       Date:  2004-05-27       Impact factor: 8.327

3.  Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China.

Authors:  Jiang-Han Wang; Wen-Lian Chen; Jun-Min Li; Song-Fang Wu; Tian-Lu Chen; Yong-Mei Zhu; Wei-Na Zhang; Yang Li; Yun-Ping Qiu; Ai-Hua Zhao; Jian-Qing Mi; Jie Jin; Yun-Gui Wang; Qiu-Ling Ma; He Huang; De-Pei Wu; Qin-Rong Wang; Yan Li; Xiao-Jing Yan; Jin-Song Yan; Jian-Yong Li; Shuai Wang; Xiao-Jun Huang; Bing-Shun Wang; Wei Jia; Yang Shen; Zhu Chen; Sai-Juan Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-30       Impact factor: 12.779
  3 in total
  20 in total

Review 1.  Metabolomic signature of brain cancer.

Authors:  Renu Pandey; Laura Caflisch; Alessia Lodi; Andrew J Brenner; Stefano Tiziani
Journal:  Mol Carcinog       Date:  2017-07-17       Impact factor: 4.784

2.  Precision oncology in the era of radiogenomics: the case of D-2HG as an imaging biomarker for mutant IDH gliomas.

Authors:  Ovidiu C Andronesi
Journal:  Neuro Oncol       Date:  2018-06-18       Impact factor: 12.300

3.  Reply to Struys: Role of biomarker of 2-hydroxyglutarate in acute myeloid leukemia.

Authors:  Yang Shen; Jing-Han Wang; Wen-Lian Chen; Wei Jia; Sai-Juan Chen; Zhu Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-17       Impact factor: 11.205

Review 4.  The Multifaceted Metabolism of Glioblastoma.

Authors:  Addison Quinones; Anne Le
Journal:  Adv Exp Med Biol       Date:  2018       Impact factor: 2.622

Review 5.  Oncometabolites in renal cancer.

Authors:  Cissy Yong; Grant D Stewart; Christian Frezza
Journal:  Nat Rev Nephrol       Date:  2019-10-21       Impact factor: 28.314

6.  Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells.

Authors:  Andrew J Worth; Kevin P Gillespie; Clementina Mesaros; Lili Guo; Sankha S Basu; Nathaniel W Snyder; Ian A Blair
Journal:  Chem Res Toxicol       Date:  2015-04-08       Impact factor: 3.739

7.  Quantitative Analysis of Oncometabolite 2-Hydroxyglutarate.

Authors:  Bi-Feng Yuan
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

8.  Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress.

Authors:  William M Oldham; Clary B Clish; Yi Yang; Joseph Loscalzo
Journal:  Cell Metab       Date:  2015-07-23       Impact factor: 27.287

Review 9.  2-Hydoxyglutarate: D/Riving Pathology in gLiomaS.

Authors:  Daniel R Wahl; Sriram Venneti
Journal:  Brain Pathol       Date:  2015-11       Impact factor: 6.508

10.  Quantification of 2-Hydroxyglutarate Enantiomers by Liquid Chromatography-mass Spectrometry.

Authors:  William M Oldham; Joseph Loscalzo
Journal:  Bio Protoc       Date:  2016-08-20
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