BACKGROUND: Applications for sentinel node biopsy (SNB) in the head and neck are increasing with new lymphatic tracers and imaging techniques allowing previously inaccessible tumor sites to benefit from the procedure. We show that lymphatic drainage from a primary parotid malignancy can be accurately mapped using navigational surgery. METHODS: A patient with radiologically classified N0 intraparotid malignancy underwent peritumoral injection of 99mTc-nanocolloid. Planar imaging and single photon emission CT (SPECT)/CT identified the sentinel node. At surgery, real-time video combined with 3 dimensional (3D) images of intraoperative radioisotope hot spots directed the surgeon to the sentinel node. RESULTS: Lymphoscintographic images demonstrated the hot nodes, which were easily retrieved intraoperatively by 3D navigation. Three lymph nodes were removed, all were free of metastasis. CONCLUSION: The morbidity associated with total parotidectomy and elective neck dissection in low-risk malignancies may be avoided with SNB. This technique is applicable to other sites within the head and neck.
BACKGROUND: Applications for sentinel node biopsy (SNB) in the head and neck are increasing with new lymphatic tracers and imaging techniques allowing previously inaccessible tumor sites to benefit from the procedure. We show that lymphatic drainage from a primary parotid malignancy can be accurately mapped using navigational surgery. METHODS: A patient with radiologically classified N0 intraparotid malignancy underwent peritumoral injection of 99mTc-nanocolloid. Planar imaging and single photon emission CT (SPECT)/CT identified the sentinel node. At surgery, real-time video combined with 3 dimensional (3D) images of intraoperative radioisotope hot spots directed the surgeon to the sentinel node. RESULTS: Lymphoscintographic images demonstrated the hot nodes, which were easily retrieved intraoperatively by 3D navigation. Three lymph nodes were removed, all were free of metastasis. CONCLUSION: The morbidity associated with total parotidectomy and elective neck dissection in low-risk malignancies may be avoided with SNB. This technique is applicable to other sites within the head and neck.
Authors: Christina Bluemel; Domenico Rubello; Patrick M Colletti; Remco de Bree; Ken Herrmann Journal: Eur J Nucl Med Mol Imaging Date: 2015-04-28 Impact factor: 9.236
Authors: Christina Bluemel; Ken Herrmann; Alexander Kübler; Andreas K Buck; Eva Geissinger; Vanessa Wild; Stefan Hartmann; Constantin Lapa; Christian Linz; Urs Müller-Richter Journal: Eur J Nucl Med Mol Imaging Date: 2014-07-31 Impact factor: 9.236