Literature DB >> 24317312

Cell adhesion molecules: druggable targets for modulating the connectome and brain disorders?

George R Uhl1, Jana Drgonova.   

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Year:  2014        PMID： 24317312      PMCID： PMC3857667          DOI： 10.1038/npp.2013.240

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


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  6 in total

1.  NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice.

Authors:  Hiroki Ishiguro; Qing-Rong Liu; Jian-Ping Gong; Frank Scott Hall; Hiroshi Ujike; Marisela Morales; Takeshi Sakurai; Martin Grumet; George R Uhl
Journal:  Neuropsychopharmacology       Date:  2006-03       Impact factor: 7.853

2.  PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome.

Authors:  Barbara Schormair; David Kemlink; Darina Roeske; Gertrud Eckstein; Lan Xiong; Peter Lichtner; Stephan Ripke; Claudia Trenkwalder; Alexander Zimprich; Karin Stiasny-Kolster; Wolfgang Oertel; Cornelius G Bachmann; Walter Paulus; Birgit Högl; Birgit Frauscher; Viola Gschliesser; Werner Poewe; Ines Peglau; Pavel Vodicka; Jana Vávrová; Karel Sonka; Sona Nevsimalova; Jacques Montplaisir; Gustavo Turecki; Guy Rouleau; Christian Gieger; Thomas Illig; H-Erich Wichmann; Florian Holsboer; Bertram Müller-Myhsok; Thomas Meitinger; Juliane Winkelmann
Journal:  Nat Genet       Date:  2008-07-27       Impact factor: 38.330

3.  Mammalian motoneuron axon targeting requires receptor protein tyrosine phosphatases sigma and delta.

Authors:  Noriko Uetani; Mélanie J Chagnon; Timothy E Kennedy; Yoichiro Iwakura; Michel L Tremblay
Journal:  J Neurosci       Date:  2006-05-31       Impact factor: 6.167

4.  T-cadherin structures reveal a novel adhesive binding mechanism.

Authors:  Carlo Ciatto; Fabiana Bahna; Niccolò Zampieri; Harper C VanSteenhouse; Phini S Katsamba; Goran Ahlsen; Oliver J Harrison; Julia Brasch; Xiangshu Jin; Shoshana Posy; Jeremie Vendome; Barbara Ranscht; Thomas M Jessell; Barry Honig; Lawrence Shapiro
Journal:  Nat Struct Mol Biol       Date:  2010-02-28       Impact factor: 15.369

Review 5.  Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects.

Authors:  George R Uhl; Tomas Drgon; Catherine Johnson; Chuan-Yun Li; Carlo Contoreggi; Judith Hess; Daniel Naiman; Qing-Rong Liu
Journal:  Ann N Y Acad Sci       Date:  2008-10       Impact factor: 5.691

6.  OKCAM: an ontology-based, human-centered knowledgebase for cell adhesion molecules.

Authors:  Chuan-Yun Li; Qing-Rong Liu; Ping-Wu Zhang; Xiao-Mo Li; Liping Wei; George R Uhl
Journal:  Nucleic Acids Res       Date:  2008-09-12       Impact factor: 16.971
  6 in total
  9 in total

1.  Mouse Model for Protein Tyrosine Phosphatase D (PTPRD) Associations with Restless Leg Syndrome or Willis-Ekbom Disease and Addiction: Reduced Expression Alters Locomotion, Sleep Behaviors and Cocaine-Conditioned Place Preference.

Authors:  Jana Drgonova; Donna Walther; Katherine J Wang; G Luke Hartstein; Bryson Lochte; Juan Troncoso; Noriko Uetani; Yoichiro Iwakura; George R Uhl
Journal:  Mol Med       Date:  2015-07-14       Impact factor: 6.354

2.  Pharmacogenetics of stimulant abuse liability: association of CDH13 variant with amphetamine response in a racially-heterogeneous sample of healthy young adults.

Authors:  Adam M Leventhal; Matthew G Kirkpatrick; Mollie S Pester; John E McGeary; Robert M Swift; Steve Sussman; Christopher W Kahler
Journal:  Psychopharmacology (Berl)       Date:  2016-10-22       Impact factor: 4.530

Review 3.  Connectome and molecular pharmacological differences in the dopaminergic system in restless legs syndrome (RLS): plastic changes and neuroadaptations that may contribute to augmentation.

Authors:  Christopher J Earley; George R Uhl; Stefan Clemens; Sergi Ferré
Journal:  Sleep Med       Date:  2016-06-27       Impact factor: 3.492

Review 4.  Human cell adhesion molecules: annotated functional subtypes and overrepresentation of addiction-associated genes.

Authors:  Xiaoming Zhong; Jana Drgonova; Chuan-Yun Li; George R Uhl
Journal:  Ann N Y Acad Sci       Date:  2015-05-18       Impact factor: 5.691

5.  Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development.

Authors:  Ian M Henderson; Fanxun Zeng; Nazmul H Bhuiyan; Dan Luo; Maria Martinez; Jane Smoake; Fangchao Bi; Chamani Perera; David Johnson; Thomas E Prisinzano; Wei Wang; George R Uhl
Journal:  Biochem Pharmacol       Date:  2021-12-02       Impact factor: 6.100

6.  Cadherin 13: human cis-regulation and selectively-altered addiction phenotypes and cerebral cortical dopamine in knockout mice.

Authors:  Jana Drgonova; Donna Walther; G Luke Hartstein; Mohammad O Bukhari; Michael H Baumann; Jonathan Katz; Frank Scott Hall; Elizabeth R Arnold; Shaun Flax; Anthony Riley; Olga Rivero-Martin; Klaus-Peter Lesch; Juan Troncoso; Barbara Ranscht; George R Uhl
Journal:  Mol Med       Date:  2016-08-18       Impact factor: 6.354

7.  Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist.

Authors:  George R Uhl; Maria J Martinez; Paul Paik; Agnieszka Sulima; Guo-Hua Bi; Malliga R Iyer; Eliot Gardner; Kenner C Rice; Zheng-Xiong Xi
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-22       Impact factor: 11.205

Review 8.  The Role of Cell Adhesion Molecule Genes Regulating Neuroplasticity in Addiction.

Authors:  Dawn E Muskiewicz; George R Uhl; F Scott Hall
Journal:  Neural Plast       Date:  2018-02-20       Impact factor: 3.599

Review 9.  Synaptic Mechanisms of Blast-Induced Brain Injury.

Authors:  Andrzej Przekwas; Mahadevabharath R Somayaji; Raj K Gupta
Journal:  Front Neurol       Date:  2016-01-21       Impact factor: 4.003
  9 in total

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