| Literature DB >> 24317049 |
Tran Manh Hung1, Nguyen Xuan Hai, Nguyen Trung Nhan, Ton That Quang, Tran Le Quan, To Dao Cuong, Nguyen Hai Dang, Nguyen Tien Dat.
Abstract
Two new phenolic compounds, caesalpiniaphenols G-H (1 and 2), were isolated from Vietnamese Caesalpinia sappan heartwood. The chemical structures were established mainly by extensive spectroscopic studies and chemical evidence. Compounds 1 and 2 showed potent inhibitory activity against HL-60 cancer cell lines with respective IC50 values of 16.7 and 22.5 µg/mL. Treating HL-60 cells with various concentrations of 1 resulted in growth inhibition and the induction of apoptosis.Entities:
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Year: 2013 PMID： 24317049 DOI： 10.1271/bbb.130493
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043