Literature DB >> 24317009

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

Anna M Rydzik1, Ivanhoe K H Leung, Armin Thalhammer, Grazyna T Kochan, Timothy D W Claridge, Christopher J Schofield.   

Abstract

A convenient method for the synthesis of fluoromethylated carnitine biosynthesis intermediates, i.e. fluorinated derivatives of γ-butyrobetaine and trimethyllysine, is described. The fluoromethylated probes were useful in both in vitro and cell based assays employing (19)F NMR and LC-MS analyses.

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Year:  2014        PMID： 24317009     DOI： 10.1039/c3cc47581f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

Review 1.  Trimethyllysine: From Carnitine Biosynthesis to Epigenetics.

Authors:  Marijn N Maas; Jordi C J Hintzen; Miriam R B Porzberg; Jasmin Mecinović
Journal:  Int J Mol Sci       Date:  2020-12-11       Impact factor: 5.923

2.  Oxygenase-catalyzed desymmetrization of N,N-dialkyl-piperidine-4-carboxylic acids.

Authors:  Anna M Rydzik; Ivanhoe K H Leung; Grazyna T Kochan; Michael A McDonough; Timothy D W Claridge; Christopher J Schofield
Journal:  Angew Chem Int Ed Engl       Date:  2014-08-27       Impact factor: 15.336
  2 in total

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