| Literature DB >> 24317 |
H Holak, A Baldys, B Jarzab, A Wystrychowski, J Skrzypek.
Abstract
The influence of various neuromediators on pituitary TSH secretion in rats has been investigated. Noradrenaline 50 microgram/rat, dopamine 50 microgram/rat, serotonine-creatinine-sulphate 100 micogram/rat, gamma-aminobutyric acid 100 microgram/rat, pilocarpine 1 mg/rat, histamine 100 microgram/rat were administered into the lateral ventricle of the brain. All agents were dissolved in Parker's fluid. Two control groups of animals were given Parker's fluid and subjected to surgical manipulations, respectively. Plasma TSH level was estimated after 30 min by means of radioimmunoassay. The increase in the TSH level was observed after the injection of serotonine and noradrenaline (4.0 and 3.1 ng/ml, respectively) as compared with control group (0.7 ng/ml).Entities:
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Year: 1978 PMID： 24317 DOI： 10.1530/acta.0.0870279
Source DB: PubMed Journal: Acta Endocrinol (Copenh) ISSN： 0001-5598