| Literature DB >> 24315366 |
Danilo B Medinas1, Claudio Hetz.
Abstract
Altered insulin signaling and neuroinflammation are emerging features of Alzheimer's disease. Lourenco et al. (2013) identify a pathogenic mechanism that is shared between Alzheimer's disease and diabetes and contributes to memory loss through a common molecular event: the control of protein synthesis by PKR and the downstream phosphorylation of eIF2α.Entities:
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Year: 2013 PMID: 24315366 DOI: 10.1016/j.cmet.2013.11.009
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287