Catarina Isabel Teixeira-Guedes1, Ana Isabel Faustino-Rocha1, Daniela Talhada1, José Alberto Duarte2, Rita Ferreira3, Fernanda Seixas4, Paula Alexandra Oliveira5. 1. Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal. 2. Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport Sciences, University of Porto, Porto, Portugal. 3. Organic Chemistry of Natural Products and Agrifood, Mass Spectrometry Center, Department of Chemistry, University of Aveiro, Aveiro, Portugal. 4. Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal; Animal and Veterinary Research Center (CECAV), University of Trás-os-Montes and Alto Douro, Vila Real, Portugal. 5. Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal; Center for the Study of Animal Sciences (CECA), University of Porto, Porto, Portugal. Electronic address: pamo@utad.pt.
Abstract
BACKGROUND: Schwannoma is a tumor of the nervous system composed by Schwann cells. It can occur naturally in several tissues of the body in both humans and animals. Diaphragmatic hernia can be congenital or acquired and is defined as a protrusion of abdominal viscera into the thoracic cavity. MATERIALS AND METHODS: The animal was a female rat from an experiment of mammary tumor chemically induced. It was injected with N-methyl-N-nitrosourea (MNU) and died spontaneously at 22 weeks of age. RESULTS: The animal had a diaphragmatic hernia and a hemorrhagic and multicystic mass in the liver herniated lobule. Microscopically the liver displayed a well circumscribed mass that was a tumor with hemorrhagic areas, necrosis and Antoni A and Antoni B patterns. It also displayed occasional positivity to vimentin and diffuse positivity to S-100 and NSE. CONCLUSION: The tumor was a schwannoma with the origin in the Glisson's capsule.
BACKGROUND:Schwannoma is a tumor of the nervous system composed by Schwann cells. It can occur naturally in several tissues of the body in both humans and animals. Diaphragmatic hernia can be congenital or acquired and is defined as a protrusion of abdominal viscera into the thoracic cavity. MATERIALS AND METHODS: The animal was a female rat from an experiment of mammary tumor chemically induced. It was injected with N-methyl-N-nitrosourea (MNU) and died spontaneously at 22 weeks of age. RESULTS: The animal had a diaphragmatic hernia and a hemorrhagic and multicystic mass in the liver herniated lobule. Microscopically the liver displayed a well circumscribed mass that was a tumor with hemorrhagic areas, necrosis and Antoni A and Antoni B patterns. It also displayed occasional positivity to vimentin and diffuse positivity to S-100 and NSE. CONCLUSION: The tumor was a schwannoma with the origin in the Glisson's capsule.