Literature DB >> 24313237

The course of sleep disturbances in early alcohol recovery: an observational cohort study.

Bhanu Prakash Kolla1, Terry Schneekloth, Joanna Biernacka, Meghna Mansukhani, Jennifer Geske, Victor Karpyak, Daniel Hall-Flavin, Larissa Louikianova, Mark A Frye.   

Abstract

INTRODUCTION: Understanding the course and determinants of sleep disturbances in alcoholic patients may help identify patients at high risk of persistent sleep problems, relapse and guide treatment interventions.
METHODS: We prospectively administered the Pittsburgh Sleep Quality Index (PSQI) to all patients (N = 196) admitted to a 1-month residential treatment program. Our analysis excluded patients with active drug abuse/dependence. Demographic data, psychiatric diagnoses, Patient Health Questionnaire-9 (PHQ-9), Alcohol Use Disorders Identification Test (AUDIT) and Inventory of Drug Taking Situations (IDTS) scores were obtained. Univariate and logistic regression analyses were performed using sex, age, hazardous alcohol use, PHQ-9 scores, hypnotic use, and use of alcohol as a hypnotic as correlates to admission PSQI scores and improvement in PSQI scores.
RESULTS: A total of 119 alcoholic patients met inclusion criteria (mean age 50.6 ± 13.2 years). The rates of sleep disturbances at admission and discharge were 69.3% and 49.1%, respectively. Self report of using alcohol to fall asleep and use of hypnotics were associated with elevated PSQI scores. Total PSQI scores improved over 4 weeks (p < .001). Change in PSQI scores was not effected by gender, use of hypnotics, hazardous alcohol use, use of alcohol as a hypnotic or co-morbid psychiatric diagnosis. Older age predicted improvement in PSQI scores in patients with sleep disturbances (p = .004).
CONCLUSION: While a large proportion of alcoholics had sleep disturbances upon admission and at discharge from a residential treatment program, only older age was associated with improvements in sleep disturbances during early alcohol recovery. © American Academy of Addiction Psychiatry.

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Year:  2013        PMID: 24313237     DOI: 10.1111/j.1521-0391.2013.12056.x

Source DB:  PubMed          Journal:  Am J Addict        ISSN: 1055-0496


  10 in total

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2.  Effect of suvorexant on event-related oscillations and EEG sleep in rats exposed to chronic intermittent ethanol vapor and protracted withdrawal.

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Review 3.  Insomnia treatment in the context of alcohol use disorder: A systematic review and meta-analysis.

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Review 4.  Alcohol Dependence and Its Relationship With Insomnia and Other Sleep Disorders.

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6.  Poor subjective sleep predicts compromised quality of life but not cognitive impairment in abstinent individuals with Alcohol Use Disorder.

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8.  Gender differences in the relationship between alcohol consumption and insomnia in the northern Chinese population.

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Review 9.  Current and potential pharmacological treatment options for insomnia in patients with alcohol use disorder in recovery.

Authors:  Timothy A Roehrs; Jessica Auciello; Jack Tseng; Garth Whiteside
Journal:  Neuropsychopharmacol Rep       Date:  2020-06-15

10.  Telemedicine-delivered cognitive-behavioral therapy for insomnia in alcohol use disorder (AUD): study protocol for a randomized controlled trial.

Authors:  J Todd Arnedt; M Elizabeth Cardoni; Deirdre A Conroy; Mandilyn Graham; Sajni Amin; Kipling M Bohnert; Andrew D Krystal; Mark A Ilgen
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  10 in total

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