Literature DB >> 24311863

A study on the inhibitory effect of matrine on gastric cancer SGC-7901 cells.

Shimao Song1, Shengming Zhu, Zhiguo Zhang, Zhengying Mo, Qing Ke, Zhiguo Luo.   

Abstract

The objective of this paper was to investigate the antitumour mechanism of action of matrine by studying its inhibitory effect on gastric cancer SGC-7901 cells. SGC-7901 cells were chosen, and cell-killing capacity of matrine on gastric cancer SGC-7901 cells was determined using MTT assay and single PI staining assay. The results showed that matrine had an inhibitory effect on gastric cancer SGC-7901 cells, which was somewhat dose-dependent. The study concluded that matrine has a significant in-vitro inhibitory effect on SGC-7901 tumour cells, influences cell cycle of SGC-7901 cells, and induces their apoptosis.

Entities:  

Keywords:  MTT assay; Matrine; SGC-7901

Mesh：

Substances：

Year:  2013        PMID： 24311863      PMCID： PMC3847378          DOI： 10.4314/ajtcam.v10i6.5

Source DB:  PubMed          Journal:  Afr J Tradit Complement Altern Med        ISSN： 2505-0044


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Review 1.  Corpse clearance defines the meaning of cell death.

Authors:  J Savill; V Fadok
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2.  Surgery for early gastric cancer: a European one-center experience.

Authors:  D Jentschura; C Heubner; B C Manegold; B Rumstadt; M Winkler; M Trede
Journal:  World J Surg       Date:  1997-10       Impact factor: 3.352

3.  Risks for respiratory and gastric cancer in wood-working occupations in Denmark.

Authors:  J H Olsen; H Møller; O M Jensen
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4.  Flow cytometric determination of apoptosis in heterogeneous cell populations.

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Review 5.  Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics.

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