Literature DB >> 24311427

PCP: thinking beyond HIV.

Alexei Gonzalez-Estrada1, James Fernandez.   

Abstract

A 40-year-old man with a previous AIDS-defining opportunistic infection and five negative HIV tests presented to our outpatient clinic. The laboratory test was relevant for less than 300 total lymphocytes on two separate occasions. He was diagnosed with idiopathic CD4 lymphocytopenia and was started on antibiotic prophylaxis for Pneumocystis carinii pneumonia and Micobacterium avium-intracellulare infection (MAI). This case report summarises the importance of further immunological characterisation in patients presenting with opportunistic infections and decreased cellular immunity.

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Year:  2013        PMID: 24311427      PMCID: PMC3863067          DOI: 10.1136/bcr-2013-201687

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  Allogeneic bone marrow transplantation can restore CD4+ T-lymphocyte count and immune function in idiopathic CD4+ T-lymphocytopenia.

Authors:  E J Petersen; M Rozenberg-Arska; A W Dekker; H C Clevers; L F Verdonck
Journal:  Bone Marrow Transplant       Date:  1996-10       Impact factor: 5.483

2.  Treatment of idiopathic CD4 T lymphocytopenia with IL-2.

Authors:  C Cunningham-Rundles; H W Murray; J P Smith
Journal:  Clin Exp Immunol       Date:  1999-05       Impact factor: 4.330

Review 3.  Idiopathic CD4 lymphocytopenia.

Authors:  Ulrich A Walker; Klaus Warnatz
Journal:  Curr Opin Rheumatol       Date:  2006-07       Impact factor: 5.006

Review 4.  Unexplained opportunistic infections and CD4+ T-lymphocytopenia without HIV infection. An investigation of cases in the United States. The Centers for Disease Control Idiopathic CD4+ T-lymphocytopenia Task Force.

Authors:  D K Smith; J J Neal; S D Holmberg
Journal:  N Engl J Med       Date:  1993-02-11       Impact factor: 91.245

  4 in total
  1 in total

1.  Severe Pneumocystis jirovecii pneumonia in an idiopathic CD4+ lymphocytopenia patient: case report and review of the literature.

Authors:  Bernabé F F Chumpitazi; Pierre Flori; Jean-Baptiste Kern; Marie-Pierre Brenier-Pinchart; Sylvie Larrat; Clémence Minet; Laurence Bouillet; Danièle Maubon; Hervé Pelloux
Journal:  JMM Case Rep       Date:  2014-12-01
  1 in total

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