OBJECTIVES: The aim of the study was to determine exposure-response relationships in salmon-processing workers. METHODS: Cross-shift FEV1, acute respiratory symptoms, and exposure to total protein, parvalbumin and endotoxin were main variables measured during one workweek. Exposure-response relationships were analyzed by Generalized Estimation Equations of cross-week data and by multiple regressions of day-to-day data. RESULTS: Exposure levels were higher in those workers who reported use of water hose. GEE showed negative coefficients for interaction between TP exposure and time (days) on cross-week change of FEV1. Multiple regressions showed significant associations between TP levels and cross-shift change of FEV1 and symptoms (cough, chest tightness) only for Monday shifts. CONCLUSIONS: A tolerance effect during the course of a workweek is suggested. Use of water hose is a risk process with regard to the liberation of measured components of bioaerosols.
OBJECTIVES: The aim of the study was to determine exposure-response relationships in salmon-processing workers. METHODS: Cross-shift FEV1, acute respiratory symptoms, and exposure to total protein, parvalbumin and endotoxin were main variables measured during one workweek. Exposure-response relationships were analyzed by Generalized Estimation Equations of cross-week data and by multiple regressions of day-to-day data. RESULTS: Exposure levels were higher in those workers who reported use of water hose. GEE showed negative coefficients for interaction between TP exposure and time (days) on cross-week change of FEV1. Multiple regressions showed significant associations between TP levels and cross-shift change of FEV1 and symptoms (cough, chest tightness) only for Monday shifts. CONCLUSIONS: A tolerance effect during the course of a workweek is suggested. Use of water hose is a risk process with regard to the liberation of measured components of bioaerosols.
Authors: Marte R Thomassen; Sandip D Kamath; Berit E Bang; Roni Nugraha; Shuai Nie; Nicholas A Williamson; Andreas L Lopata; Lisbeth Aasmoe Journal: Front Allergy Date: 2021-08-23
Authors: Gro Tjalvin; Øistein Svanes; Randi Jacobsen Bertelsen; Bjørg Eli Hollund; Tor B Aasen; Cecilie Svanes; Jorunn Kirkeleit Journal: ERJ Open Res Date: 2018-10-03