Literature DB >> 24309839

Fingolimod-induced atrioventricular conduction defects in a young lady with multiple sclerosis--insights into possible drug mechanism.

Victor Voon1, Lavanya Saiva, Sara O'Kelly, David Keane.   

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Year:  2013        PMID: 24309839     DOI: 10.1007/s00228-013-1620-7

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


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  19 in total

1.  Placebo-controlled study of the effects of fingolimod on cardiac rate and rhythm and pulmonary function in healthy volunteers.

Authors:  Robert Schmouder; Sam Hariry; Olivier J David
Journal:  Eur J Clin Pharmacol       Date:  2011-11-10       Impact factor: 2.953

2.  Prolonged and symptomatic bradycardia following a single dose of fingolimod.

Authors:  Hans Faber; Hans-Jörg Fischer; Frank Weber
Journal:  Mult Scler       Date:  2012-06-22       Impact factor: 6.312

3.  Oral fingolimod (FTY720) for relapsing multiple sclerosis.

Authors:  Ludwig Kappos; Jack Antel; Giancarlo Comi; Xavier Montalban; Paul O'Connor; Chris H Polman; Tomas Haas; Alexander A Korn; Goeril Karlsson; Ernst W Radue
Journal:  N Engl J Med       Date:  2006-09-14       Impact factor: 91.245

4.  Fingolimod provides long-term protection in rodent models of cerebral ischemia.

Authors:  Ying Wei; Muge Yemisci; Hyung-Hwan Kim; Lai Ming Yung; Hwa Kyoung Shin; Seo-Kyoung Hwang; Shuzhen Guo; Tao Qin; Nafiseh Alsharif; Volker Brinkmann; James K Liao; Eng H Lo; Christian Waeber
Journal:  Ann Neurol       Date:  2010-11-12       Impact factor: 10.422

5.  Fingolimod and cardiac risk: latest findings and clinical implications.

Authors:  Wendy S Vargas; Jai S Perumal
Journal:  Ther Adv Drug Saf       Date:  2013-06

Review 6.  Sphingosine-1-phosphate signaling in the cardiovascular system.

Authors:  Stephan L M Peters; Astrid E Alewijnse
Journal:  Curr Opin Pharmacol       Date:  2007-02-05       Impact factor: 5.547

Review 7.  Sphingolipid signalling in the cardiovascular system: good, bad or both?

Authors:  Astrid E Alewijnse; Stephan L M Peters
Journal:  Eur J Pharmacol       Date:  2008-03-15       Impact factor: 4.432

Review 8.  FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system.

Authors:  Volker Brinkmann
Journal:  Br J Pharmacol       Date:  2009-10-08       Impact factor: 8.739

9.  A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation.

Authors:  S Suzuki; S Enosawa; T Kakefuda; T Shinomiya; M Amari; S Naoe; Y Hoshino; K Chiba
Journal:  Transplantation       Date:  1996-01-27       Impact factor: 4.939

10.  Protective effects of sphingosine-1-phosphate receptor agonist treatment after myocardial ischaemia-reperfusion.

Authors:  Ulrich Hofmann; Natalie Burkard; Carolin Vogt; Annemarie Thoma; Stefan Frantz; Georg Ertl; Oliver Ritter; Andreas Bonz
Journal:  Cardiovasc Res       Date:  2009-05-05       Impact factor: 10.787

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