Literature DB >> 24309653

Metformin trims fats to restore insulin sensitivity.

Reuben J Shaw1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24309653     DOI： 10.1038/nm.3414

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


× No keyword cloud information.
  16 in total

1.  Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.

Authors:  M R Owen; E Doran; A P Halestrap
Journal:  Biochem J       Date:  2000-06-15       Impact factor: 3.857

Review 2.  AMPK: a nutrient and energy sensor that maintains energy homeostasis.

Authors:  D Grahame Hardie; Fiona A Ross; Simon A Hawley
Journal:  Nat Rev Mol Cell Biol       Date:  2012-03-22       Impact factor: 94.444

3.  Mechanism by which metformin reduces glucose production in type 2 diabetes.

Authors:  R S Hundal; M Krssak; S Dufour; D Laurent; V Lebon; V Chandramouli; S E Inzucchi; W C Schumann; K F Petersen; B R Landau; G I Shulman
Journal:  Diabetes       Date:  2000-12       Impact factor: 9.461

4.  Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver.

Authors:  Marc Foretz; Nicolas Ancellin; Fabrizio Andreelli; Yannick Saintillan; Pascal Grondin; Axel Kahn; Bernard Thorens; Sophie Vaulont; Benoît Viollet
Journal:  Diabetes       Date:  2005-05       Impact factor: 9.461

Review 5.  The AMPK signalling pathway coordinates cell growth, autophagy and metabolism.

Authors:  Maria M Mihaylova; Reuben J Shaw
Journal:  Nat Cell Biol       Date:  2011-09-02       Impact factor: 28.824

6.  Role of AMP-activated protein kinase in mechanism of metformin action.

Authors:  G Zhou; R Myers; Y Li; Y Chen; X Shen; J Fenyk-Melody; M Wu; J Ventre; T Doebber; N Fujii; N Musi; M F Hirshman; L J Goodyear; D E Moller
Journal:  J Clin Invest       Date:  2001-10       Impact factor: 14.808

7.  Chronic activation of AMP-activated protein kinase-alpha1 in liver leads to decreased adiposity in mice.

Authors:  Jian Yang; Shanna Maika; Lauren Craddock; Judy A King; Zhi-Mei Liu
Journal:  Biochem Biophys Res Commun       Date:  2008-03-31       Impact factor: 3.575

Review 8.  AMPK in Health and Disease.

Authors:  Gregory R Steinberg; Bruce E Kemp
Journal:  Physiol Rev       Date:  2009-07       Impact factor: 37.312

9.  Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.

Authors:  Russell A Miller; Qingwei Chu; Jianxin Xie; Marc Foretz; Benoit Viollet; Morris J Birnbaum
Journal:  Nature       Date:  2013-01-06       Impact factor: 49.962

Review 10.  Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance.

Authors:  François R Jornayvaz; Gerald I Shulman
Journal:  Cell Metab       Date:  2012-05-02       Impact factor: 27.287
View more
  11 in total

1.  Maslinic acid protects against obesity-induced nonalcoholic fatty liver disease in mice through regulation of the Sirt1/AMPK signaling pathway.

Authors:  Chian-Jiun Liou; Yi-Wen Dai; Chia-Ling Wang; Li-Wen Fang; Wen-Chung Huang
Journal:  FASEB J       Date:  2019-07-30       Impact factor: 5.191

Review 2.  Systematic review: Preventive and therapeutic applications of metformin in liver disease.

Authors:  Aparna Bhat; Giada Sebastiani; Mamatha Bhat
Journal:  World J Hepatol       Date:  2015-06-28

3.  The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.

Authors:  Changhan Lee; Jennifer Zeng; Brian G Drew; Tamer Sallam; Alejandro Martin-Montalvo; Junxiang Wan; Su-Jeong Kim; Hemal Mehta; Andrea L Hevener; Rafael de Cabo; Pinchas Cohen
Journal:  Cell Metab       Date:  2015-03-03       Impact factor: 27.287

Review 4.  Metformin and metabolic diseases: a focus on hepatic aspects.

Authors:  Juan Zheng; Shih-Lung Woo; Xiang Hu; Rachel Botchlett; Lulu Chen; Yuqing Huo; Chaodong Wu
Journal:  Front Med       Date:  2015-02-12       Impact factor: 4.592

5.  Houttuynia cordata Facilitates Metformin on Ameliorating Insulin Resistance Associated with Gut Microbiota Alteration in OLETF Rats.

Authors:  Jing-Hua Wang; Shambhunath Bose; Soo-Kyoung Lim; AbuZar Ansari; Young-Won Chin; Han Seok Choi; Hojun Kim
Journal:  Genes (Basel)       Date:  2017-09-22       Impact factor: 4.096

6.  Effect of metformin monotherapy on serum lipid profile in statin-naïve individuals with newly diagnosed type 2 diabetes mellitus: a cohort study.

Authors:  Szu Han Lin; Po Chung Cheng; Shih Te Tu; Shang Ren Hsu; Yun Chung Cheng; Yu Hsiu Liu
Journal:  PeerJ       Date:  2018-04-12       Impact factor: 2.984

7.  AICAR decreases acute lung injury by phosphorylating AMPK and upregulating heme oxygenase-1.

Authors:  Israr Ahmad; Adam Molyvdas; Ming-Yuan Jian; Ting Zhou; Amie M Traylor; Huachun Cui; Gang Liu; Weifeng Song; Anupam Agarwal; Tamas Jilling; Saurabh Aggarwal; Sadis Matalon
Journal:  Eur Respir J       Date:  2021-12-23       Impact factor: 33.795

8.  Ginkgolide C Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway.

Authors:  Chian-Jiun Liou; Xuan-Yu Lai; Ya-Ling Chen; Chia-Ling Wang; Ciao-Han Wei; Wen-Chung Huang
Journal:  Evid Based Complement Alternat Med       Date:  2015-08-30       Impact factor: 2.629

9.  Metformin ameliorates the Phenotype Transition of Peritoneal Mesothelial Cells and Peritoneal Fibrosis via a modulation of Oxidative Stress.

Authors:  Hyun-Soo Shin; Jiyeon Ko; Dal-Ah Kim; Eun-Sun Ryu; Hye-Myung Ryu; Sun-Hee Park; Yong-Lim Kim; Eok-Soo Oh; Duk-Hee Kang
Journal:  Sci Rep       Date:  2017-07-18       Impact factor: 4.379

10.  Metformin reverses established lung fibrosis in a bleomycin model.

Authors:  Sunad Rangarajan; Nathaniel B Bone; Anna A Zmijewska; Shaoning Jiang; Dae Won Park; Karen Bernard; Morgan L Locy; Saranya Ravi; Jessy Deshane; Roslyn B Mannon; Edward Abraham; Victor Darley-Usmar; Victor J Thannickal; Jaroslaw W Zmijewski
Journal:  Nat Med       Date:  2018-07-02       Impact factor: 53.440
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.