Literature DB >> 24309651

It has to be the αv: myofibroblast integrins activate latent TGF-β1.

Boris Hinz1.   

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Year:  2013        PMID： 24309651     DOI： 10.1038/nm.3421

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  15 in total

1.  Latent TGF-β structure and activation.

Authors:  Minlong Shi; Jianghai Zhu; Rui Wang; Xing Chen; Lizhi Mi; Thomas Walz; Timothy A Springer
Journal:  Nature       Date:  2011-06-15       Impact factor: 49.962

2.  A novel fibronectin receptor with an unexpected subunit composition (alpha v beta 1).

Authors:  B E Vogel; G Tarone; F G Giancotti; J Gailit; E Ruoslahti
Journal:  J Biol Chem       Date:  1990-04-15       Impact factor: 5.157

3.  The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

Authors:  J S Munger; X Huang; H Kawakatsu; M J Griffiths; S L Dalton; J Wu; J F Pittet; N Kaminski; C Garat; M A Matthay; D B Rifkin; D Sheppard
Journal:  Cell       Date:  1999-02-05       Impact factor: 41.582

4.  Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1.

Authors:  J S Munger; J G Harpel; F G Giancotti; D B Rifkin
Journal:  Mol Biol Cell       Date:  1998-09       Impact factor: 4.138

Review 5.  Targeting the TGFβ signalling pathway in disease.

Authors:  Rosemary J Akhurst; Akiko Hata
Journal:  Nat Rev Drug Discov       Date:  2012-09-24       Impact factor: 84.694

6.  Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation.

Authors:  Gerald S Horan; Susan Wood; Victor Ona; Dan Jun Li; Matvey E Lukashev; Paul H Weinreb; Kenneth J Simon; Kyungmin Hahm; Normand E Allaire; Nicola J Rinaldi; Jaya Goyal; Carol A Feghali-Bostwick; Eric L Matteson; Carl O'Hara; Robert Lafyatis; Gerald S Davis; Xiaozhu Huang; Dean Sheppard; Shelia M Violette
Journal:  Am J Respir Crit Care Med       Date:  2007-10-04       Impact factor: 21.405

7.  Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis.

Authors:  Tatiana Kisseleva; Min Cong; Yonghan Paik; David Scholten; Chunyan Jiang; Chris Benner; Keiko Iwaisako; Thomas Moore-Morris; Brian Scott; Hidekazu Tsukamoto; Sylvia M Evans; Wolfgang Dillmann; Christopher K Glass; David A Brenner
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-07       Impact factor: 11.205

Review 8.  Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activation.

Authors:  Ian B Robertson; Daniel B Rifkin
Journal:  Cytokine Growth Factor Rev       Date:  2013-07-12       Impact factor: 7.638

9.  The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1.

Authors:  Dezhi Mu; Stephanie Cambier; Lars Fjellbirkeland; Jody L Baron; John S Munger; Hisaaki Kawakatsu; Dean Sheppard; V Courtney Broaddus; Stephen L Nishimura
Journal:  J Cell Biol       Date:  2002-04-22       Impact factor: 10.539

10.  Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.

Authors:  Christine C Hsu; Juliane S Troeger; Ingmar Mederacke; Peter Huebener; Xueru Mu; Dianne H Dapito; Jean-Philippe Pradere; Robert F Schwabe
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919
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  23 in total

1.  Inflammation Drives Retraction, Stiffening, and Nodule Formation via Cytoskeletal Machinery in a Three-Dimensional Culture Model of Aortic Stenosis.

Authors:  Jina Lim; Arshia Ehsanipour; Jeffrey J Hsu; Jinxiu Lu; Taylor Pedego; Alexander Wu; Chris M Walthers; Linda L Demer; Stephanie K Seidlits; Yin Tintut
Journal:  Am J Pathol       Date:  2016-07-05       Impact factor: 4.307

2.  COMP-lex Mechanics: Matricrine Signaling.

Authors:  Yin Tintut; Linda L Demer
Journal:  Circ Res       Date:  2016-07-08       Impact factor: 17.367

Review 3.  The pericyte microenvironment during vascular development.

Authors:  Laura B Payne; Huaning Zhao; Carissa C James; Jordan Darden; David McGuire; Sarah Taylor; James W Smyth; John C Chappell
Journal:  Microcirculation       Date:  2019-05-27       Impact factor: 2.628

4.  Activation of latent TGFβ by αvβ 1 integrin: of potential importance in myofibroblast activation in fibrosis.

Authors:  Andrew Leask; James Hutchenreuther
Journal:  J Cell Commun Signal       Date:  2014-01-24       Impact factor: 5.782

5.  Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation.

Authors:  Casimiro Gerarduzzi; Ramya K Kumar; Priyanka Trivedi; Amrendra K Ajay; Ashwin Iyer; Sarah Boswell; John N Hutchinson; Sushrut S Waikar; Vishal S Vaidya
Journal:  JCI Insight       Date:  2017-04-20

6.  Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction.

Authors:  Vincent Sarrazy; Anne Koehler; Melissa L Chow; Elena Zimina; Chen X Li; Hideyuki Kato; Christopher A Caldarone; Boris Hinz
Journal:  Cardiovasc Res       Date:  2014-03-17       Impact factor: 10.787

Review 7.  Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins.

Authors:  Ian B Robertson; Daniel B Rifkin
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-06-01       Impact factor: 10.005

8.  Mechanoregulation of Myofibroblast Fate and Cardiac Fibrosis.

Authors:  Peter Kim; Nick Chu; Jennifer Davis; Deok-Ho Kim
Journal:  Adv Biosyst       Date:  2017-12-04

Review 9.  Mechanobiology of myofibroblast adhesion in fibrotic cardiac disease.

Authors:  Alison K Schroer; W David Merryman
Journal:  J Cell Sci       Date:  2015-04-27       Impact factor: 5.285

10.  Premacular membranes in tissue culture.

Authors:  Denise Vogt; Franziska Vielmuth; Christian Wertheimer; Felix Hagenau; Stefanie R Guenther; Armin Wolf; Volker Spindler; Siegfried G Priglinger; Ricarda G Schumann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-06-21       Impact factor: 3.117
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