BACKGROUND AND PURPOSE: Current surgical decision-making is overly subjective and often misjudges a patient's physiologic state. The concept of frailty has gained recent recognition and potentially represents a measureable phenotype, which can quantify a patient's physiologic reserve and risk of an adverse surgical outcome. We sought to investigate the relationship between preoperative markers of frailty and postoperative complications in patients undergoing minimally invasive surgery (MIS). METHODS: Frailty, using the methodology described by Fried and coworkers, was prospectively measured in patients who presented to urology, general surgery, and surgical oncology clinics where major MIS (endoscopic, laparoscopic, or robotic) was planned. The relationship between preoperative markers of frailty and 30-day postoperative complications was our primary outcome measure. RESULTS: Our cohort includes 80 patients. Mean age and body mass index were 60.0 (range 19-87) years and 29.2 (range 18.4-53.1) kg/m(2), respectively. The majority of patients were male (57.5%) and Caucasian (65.0%). Thirteen patients were deemed "intermediately frail" or "frail," and the remaining 67 were classified as "not frail." Thirteen (16.25%) patients experienced any postoperative complication. Five (38.5%) of the intermediately frail and frail patients experienced a complication, compared with eight (11.9%) of the not frail patients (odds ratio=5.914; 95% confidence interval=1.25-27.96; P=0.025). CONCLUSION: The advent of MIS has potentially lured surgeons into thinking older and patients with comorbidities may more easily tolerate this surgical approach compared with traditional open techniques. Our data suggest, however, that intermediately frail or frail patients are at increased risk of experiencing postoperative complications compared with not frail patients.
BACKGROUND AND PURPOSE: Current surgical decision-making is overly subjective and often misjudges a patient's physiologic state. The concept of frailty has gained recent recognition and potentially represents a measureable phenotype, which can quantify a patient's physiologic reserve and risk of an adverse surgical outcome. We sought to investigate the relationship between preoperative markers of frailty and postoperative complications in patients undergoing minimally invasive surgery (MIS). METHODS: Frailty, using the methodology described by Fried and coworkers, was prospectively measured in patients who presented to urology, general surgery, and surgical oncology clinics where major MIS (endoscopic, laparoscopic, or robotic) was planned. The relationship between preoperative markers of frailty and 30-day postoperative complications was our primary outcome measure. RESULTS: Our cohort includes 80 patients. Mean age and body mass index were 60.0 (range 19-87) years and 29.2 (range 18.4-53.1) kg/m(2), respectively. The majority of patients were male (57.5%) and Caucasian (65.0%). Thirteen patients were deemed "intermediately frail" or "frail," and the remaining 67 were classified as "not frail." Thirteen (16.25%) patients experienced any postoperative complication. Five (38.5%) of the intermediately frail and frail patients experienced a complication, compared with eight (11.9%) of the not frail patients (odds ratio=5.914; 95% confidence interval=1.25-27.96; P=0.025). CONCLUSION: The advent of MIS has potentially lured surgeons into thinking older and patients with comorbidities may more easily tolerate this surgical approach compared with traditional open techniques. Our data suggest, however, that intermediately frail or frail patients are at increased risk of experiencing postoperative complications compared with not frail patients.
Authors: Anne M Suskind; Chengshi Jin; Matthew R Cooperberg; Emily Finlayson; W John Boscardin; Saunak Sen; Louise C Walter Journal: Urology Date: 2016-07-05 Impact factor: 2.649
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Authors: Katharina Anic; Friedrich Flohr; Mona Wanda Schmidt; Slavomir Krajnak; Roxana Schwab; Marcus Schmidt; Christiane Westphalen; Clemens Eichelsbacher; Christian Ruckes; Walburgis Brenner; Annette Hasenburg; Marco Johannes Battista Journal: J Cancer Res Clin Oncol Date: 2022-05-17 Impact factor: 4.553
Authors: Lucia Ilaria Sgaramella; Angela Gurrado; Alessandro Pasculli; Nicola de Angelis; Riccardo Memeo; Francesco Paolo Prete; Stefano Berti; Graziano Ceccarelli; Marco Rigamonti; Francesco Giuseppe Aldo Badessi; Nicola Solari; Marco Milone; Fausto Catena; Stefano Scabini; Francesco Vittore; Gennaro Perrone; Carlo de Werra; Ferdinando Cafiero; Mario Testini Journal: Surg Endosc Date: 2020-08-11 Impact factor: 4.584