Literature DB >> 24305096

[Long-term outcomes of ileal pouch-anal canal anastomosis in children with ulcerative colitis].

Kenji Tatsumi1, Akira Sugita, Kazutaka Koganei, Ryo Futatsuki, Hirosuke Kuroki, Kyoko Yamada, Sayumi Nakao, Minako Sako, Hideaki Kimura, Katsuhiko Arai, Tsuneo Fukushima.   

Abstract

The present study investigated the long-term outcomes of restorative proctocolectomy in pediatric patients with ulcerative colitis (UC). We report a series of 25 patients who underwent total proctocolectomy with ileal pouch-anal canal anastomosis (IACA). Surgery was performed for medically intractable colitis and severe colitis in 14 and 11 patients, respectively. Early and late complications were observed in 6 (24%) and 14 (56%) patients, respectively. The long-term quality of life outcomes were satisfactory, including both bowel function and social function. Growth retardation was observed in 6 patients. Five patients exhibited catch-up growth and 3 patients overcame growth retardation. Patients with growth retardation tended to have a younger onset and longer duration of UC, as well as a longer duration and higher total dose of steroid use. In conclusion, the long-term outcomes of pediatric patients with UC undergoing IACA are satisfactory. Furthermore, to minimize the risk of growth retardation, surgery should be performed without delay.

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Year:  2013        PMID: 24305096

Source DB:  PubMed          Journal:  Nihon Shokakibyo Gakkai Zasshi        ISSN: 0446-6586


  1 in total

1.  Gastrointestinal endoscopy biopsy derived proteomic patterns predict indeterminate colitis into ulcerative colitis and Crohn's colitis.

Authors:  Billy Ray Ballard; Amosy Ephreim M'Koma
Journal:  World J Gastrointest Endosc       Date:  2015-06-25
  1 in total

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