| Literature DB >> 24304318 |
Luz Mayela Soto-Jimenez, Karel Estrada, Alejandro Sanchez-Flores1.
Abstract
Over the past decades DNA sequencing technologies have been improving in aspects like quality, read length, runtimes and yields, all at a lower cost. Despite these improvements, genome assembly remains a challenge in genome sequencing projects, especially when different sequencing platforms are used. At the present, there is no program that can handle and assemble different sequencing technologies better than specialized software for each of them. Also, very few protocols are available for merging results from different algorithms, technologies or both. We present GARM, (Genome Assembler, Reconciliation and Merging) a pipeline to merge assemblies from different algorithms or sequencing technologies.Mesh:
Year: 2014 PMID: 24304318 DOI: 10.2174/1568026613666131204110628
Source DB: PubMed Journal: Curr Top Med Chem ISSN: 1568-0266 Impact factor: 3.295