Literature DB >> 2430288

A Drosophila mutation that eliminates a calcium-dependent potassium current.

T Elkins, B Ganetzky, C F Wu.   

Abstract

A mutation of Drosophila, slowpoke (slo), specifically abolishes a Ca2+-dependent K+ current, IC, from dorsal longitudinal flight muscles of adult flies. Other K+ currents remain normal, providing evidence that IC is mediated by a molecularly distinguishable set of channels. The pharmacological properties of IC are similar to those of Ca2+-dependent currents in some vertebrate cells. The muscle action potential was significantly lengthened in slo flies, indicating that IC plays the major role in its repolarization.

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Year:  1986        PMID： 2430288      PMCID： PMC386939          DOI： 10.1073/pnas.83.21.8415

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  28 in total

1.  Apamin blocks certain neurotransmitter-induced increases in potassium permeability.

Authors:  B E Banks; C Brown; G M Burgess; G Burnstock; M Claret; T M Cocks; D H Jenkinson
Journal:  Nature       Date:  1979-11-22       Impact factor: 49.962

2.  Voltage clamp analysis of membrane currents in larval muscle fibers of Drosophila: alteration of potassium currents in Shaker mutants.

Authors:  C F Wu; F N Haugland
Journal:  J Neurosci       Date:  1985-10       Impact factor: 6.167

3.  Two mutations of synaptic transmission in Drosophila.

Authors:  Y N Jan; L Y Jan; M J Dennis
Journal:  Proc R Soc Lond B Biol Sci       Date:  1977-07-28

4.  Drosophila mutants with opposing effects on nerve excitability: genetic and spatial interactions in repetitive firing.

Authors:  B Ganetzky; C F Wu
Journal:  J Neurophysiol       Date:  1982-03       Impact factor: 2.714

5.  Genetic modification of potassium channels in Drosophila Shaker mutants.

Authors:  L Salkoff; R Wyman
Journal:  Nature       Date:  1981 Sep 17-23       Impact factor: 49.962

6.  Drosophila mutants reveal two components of fast outward current.

Authors:  L Salkoff
Journal:  Nature       Date:  1983 Mar 17-23       Impact factor: 49.962

7.  Potassium current suppression by quinidine reveals additional calcium currents in neuroblastoma cells.

Authors:  M C Fishman; I Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

8.  Neurogenetic analysis of potassium currents in Drosophila: synergistic effects on neuromuscular transmission in double mutants.

Authors:  B Ganetzky; C F Wu
Journal:  J Neurogenet       Date:  1983-09       Impact factor: 1.250

9.  Three pharmacologically distinct potassium channels in molluscan neurones.

Authors:  S H Thompson
Journal:  J Physiol       Date:  1977-02       Impact factor: 5.182

10.  A 'TEA+-insensitive' mutant with increased potassium conductance in Paramecium aurelia.

Authors:  Y Satow; C Kung
Journal:  J Exp Biol       Date:  1976-08       Impact factor: 3.312
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  85 in total

1.  Molecular separation of two behavioral phenotypes by a mutation affecting the promoters of a Ca-activated K channel.

Authors:  N S Atkinson; R Brenner; W m Chang; J Wilbur; J L Larimer; J Yu
Journal:  J Neurosci       Date:  2000-04-15       Impact factor: 6.167

2.  An in vitro method for recording the electrical activity of the isolated heart of the adult Drosophila melanogaster.

Authors:  C Papaefthmiou; G Theophilidis
Journal:  In Vitro Cell Dev Biol Anim       Date:  2001 Jul-Aug       Impact factor: 2.416

3.  A novel leg-shaking Drosophila mutant defective in a voltage-gated K(+)current and hypersensitive to reactive oxygen species.

Authors:  J W Wang; J M Humphreys; J P Phillips; A J Hilliker; C F Wu
Journal:  J Neurosci       Date:  2000-08-15       Impact factor: 6.167

4.  Interactions of membrane excitability mutations affecting potassium and sodium currents in the flight and giant fiber escape systems of Drosophila.

Authors:  J E Engel; C F Wu
Journal:  J Comp Physiol A       Date:  1992-08       Impact factor: 1.836

Review 5.  An unexpected journey: conceptual evolution of mechanoregulated potassium transport in the distal nephron.

Authors:  Rolando Carrisoza-Gaytan; Marcelo D Carattino; Thomas R Kleyman; Lisa M Satlin
Journal:  Am J Physiol Cell Physiol       Date:  2015-12-02       Impact factor: 4.249

Review 6.  A BK (Slo1) channel journey from molecule to physiology.

Authors:  Gustavo F Contreras; Karen Castillo; Nicolás Enrique; Willy Carrasquel-Ursulaez; Juan Pablo Castillo; Verónica Milesi; Alan Neely; Osvaldo Alvarez; Gonzalo Ferreira; Carlos González; Ramón Latorre
Journal:  Channels (Austin)       Date:  2013-09-11       Impact factor: 2.581

7.  Cytosolic calcium coordinates mitochondrial energy metabolism with presynaptic activity.

Authors:  Amit K Chouhan; Maxim V Ivannikov; Zhongmin Lu; Mutsuyuki Sugimori; Rodolfo R Llinas; Gregory T Macleod
Journal:  J Neurosci       Date:  2012-01-25       Impact factor: 6.167

8.  Flight and seizure motor patterns in Drosophila mutants: simultaneous acoustic and electrophysiological recordings of wing beats and flight muscle activity.

Authors:  Atulya Iyengar; Chun-Fang Wu
Journal:  J Neurogenet       Date:  2014 Sep-Dec       Impact factor: 1.250

9.  Sodium-dependent potassium channels in leech P neurons.

Authors:  G Klees; P Hochstrate; P W Dierkes
Journal:  J Membr Biol       Date:  2005-11       Impact factor: 1.843

10.  A cyclic AMP-activated K+ channel in Drosophila larval muscle is persistently activated in dunce.

Authors:  R Delgado; P Hidalgo; F Diaz; R Latorre; P Labarca
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-15       Impact factor: 11.205
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