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Literature DB >> 24302770

Pomalidomide is strongly antiangiogenic and teratogenic in relevant animal models.

Robert J D'Amato¹, Suzanne Lentzsch, Michael S Rogers.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2013 PMID： 24302770 PMCID： PMC3864340 DOI： 10.1073/pnas.1315875110

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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4 in total

1. Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro.

Authors: Chris Mahony; Lynda Erskine; Jennifer Niven; Nigel H Greig; William Douglas Figg; Neil Vargesson
Journal: Proc Natl Acad Sci U S A Date: 2013-07-15 Impact factor: 11.205

2. Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

Authors: Yuan Xiao Zhu; Esteban Braggio; Chang-Xin Shi; Laura A Bruins; Jessica E Schmidt; Scott Van Wier; Xiu-Bao Chang; Chad C Bjorklund; Rafael Fonseca; P Leif Bergsagel; Robert Z Orlowski; A Keith Stewart
Journal: Blood Date: 2011-08-22 Impact factor: 22.113

3. Identification of a primary target of thalidomide teratogenicity.

Authors: Takumi Ito; Hideki Ando; Takayuki Suzuki; Toshihiko Ogura; Kentaro Hotta; Yoshimasa Imamura; Yuki Yamaguchi; Hiroshi Handa
Journal: Science Date: 2010-03-12 Impact factor: 47.728

4. S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice.

Authors: Suzanne Lentzsch; Michael S Rogers; Richard LeBlanc; Amy E Birsner; Jamshed H Shah; Anthony M Treston; Kenneth C Anderson; Robert J D'Amato
Journal: Cancer Res Date: 2002-04-15 Impact factor: 12.701

4 in total

3 in total

Pomalidomide is strongly antiangiogenic and teratogenic in relevant animal models.

1. Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro.

2. Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

3. Identification of a primary target of thalidomide teratogenicity.

4. S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice.

1. Reply to D’Amato et al. and Zeldis et al.: Screening of thalidomide derivatives in chicken and zebrafish embryos.

2. The thalidomide-binding domain of cereblon defines the CULT domain family and is a new member of the β-tent fold.

Review 3. (Lymph)angiogenic influences on hematopoietic cells in acute myeloid leukemia.