Literature DB >> 24301426

Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia: results from the CEPHEUS study in Arabian Gulf countries.

Mohamed Arafah1, Ali T Al-Hinai2, Wael Al Mahmeed3, Khalid Al-Rasadi4, Omer Al Tamimi5, Shorook Al Herz6, Faisal Al Anazi7, Khalid Al Nemer8, Othman Metwally9, Akram Alkhadra10, Mohammed Fakhry10, Hossam Elghetany11, Abdel Razak Medani12, Afzal Hussein Yusufali12, Obaid Al Jassim12, Omar Al Hallaq13, Fahad Omar Ahmed S Baslaib14, Mahmoud Alawadhi15, Haitham Amin16, Khamis Al-Hashmi2, Abdullah Shehab17.   

Abstract

The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age<40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.
© The Author(s) 2013.

Entities:  

Keywords:  Arabian Gulf countries; cardiovascular; coronary; guidelines; hypercholesterolemia; lipids; low-density lipoprotein

Mesh:

Substances:

Year:  2013        PMID: 24301426     DOI: 10.1177/0003319713512414

Source DB:  PubMed          Journal:  Angiology        ISSN: 0003-3197            Impact factor:   3.619


  16 in total

1.  Dyslipidemia in the Arabian Gulf and its Impact on Cardiovascular Risk Outcome.

Authors:  Khalid Al-Rasadi; Hilal Al-Sabti
Journal:  Oman Med J       Date:  2015-11

Review 2.  Cardiovascular disease in the Eastern Mediterranean region: epidemiology and risk factor burden.

Authors:  Karam Turk-Adawi; Nizal Sarrafzadegan; Ibtihal Fadhil; Kathryn Taubert; Masoumeh Sadeghi; Nanette K Wenger; Nigel S Tan; Sherry L Grace
Journal:  Nat Rev Cardiol       Date:  2017-09-21       Impact factor: 32.419

3.  Centralized Pan-Middle East Survey on the Under-Treatment of Hypercholesterolemia: Results from the CEPHEUS Study in Egypt.

Authors:  A Reda; A A Abdel-Rehim; A Etman; O S A Afifi
Journal:  Cardiol Ther       Date:  2014-11-18

Review 4.  Unmet need in the hyperlipidaemia population with high risk of cardiovascular disease: a targeted literature review of observational studies.

Authors:  S Mitchell; S Roso; M Samuel; M Pladevall-Vila
Journal:  BMC Cardiovasc Disord       Date:  2016-04-26       Impact factor: 2.298

5.  Assessment of physicians' awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?

Authors:  Mohammed Ali Batais; Turky H Almigbal; Aref A Bin Abdulhak; Hani B Altaradi; Khalid F AlHabib
Journal:  PLoS One       Date:  2017-08-17       Impact factor: 3.240

6.  Sex disparity in the management and outcomes of dyslipidemia of diabetic patients in the Arabian Gulf: findings from the CEPHEUS study.

Authors:  Ibrahim Al-Zakwani; Fatma Al-Mahruqi; Khalid Al-Rasadi; Abdullah Shehab; Wael Al Mahmeed; Mohammed Arafah; Ali T Al-Hinai; Omer Al Tamimi; Mahmoud Al Awadhi; Raul D Santos
Journal:  Lipids Health Dis       Date:  2018-02-05       Impact factor: 3.876

7.  Assessment of medical intern's knowledge, awareness and practice of familial hypercholesterolemia at academic institutes in Jeddah, Saudi Arabia.

Authors:  Sami H Alzahrani; Abdulhadi Bima; Mohammed R Algethami; Zuhier Awan
Journal:  Lipids Health Dis       Date:  2020-05-21       Impact factor: 3.876

8.  Impact of metabolic syndrome on lipid target achievements in the Arabian Gulf: findings from the CEPHEUS study.

Authors:  Ibrahim Al-Zakwani; Wael Al Mahmeed; Abdullah Shehab; Mohamed Arafah; Ali T Al-Hinai; Omer Al Tamimi; Mahmoud Al Awadhi; Shorook Al Herz; Faisal Al Anazi; Khalid Al Nemer; Othman Metwally; Akram Alkhadra; Mohammed Fakhry; Hossam Elghetany; Abdel Razak Medani; Afzal Hussein Yusufali; Obaid Al Jassim; Omar Al Hallaq; Fahad Omar Ahmed S Baslaib; Haitham Amin; Khalid Al-Waili; Khamis Al-Hashmi; Raul D Santos; Khalid Al-Rasadi
Journal:  Diabetol Metab Syndr       Date:  2016-07-26       Impact factor: 3.320

9.  Control of Risk Factors for Cardiovascular Disease among Multinational Patient Population in the Arabian Gulf.

Authors:  Ibrahim Al-Zakwani; Wael Al-Mahmeed; Mohamed Arafah; Ali T Al-Hinai; Abdullah Shehab; Omer Al-Tamimi; Mahmoud Al-Awadhi; Shorook Al-Herz; Faisal Al-Anazi; Khalid Al-Nemer; Othman Metwally; Akram Al-Khadra; Mohammed Fakhry; Hossam Elghetany; Abdel R Medani; Afzal H Yusufali; Obaid Al-Jassim; Omar Al-Hallaq; Fahad O A S Baslaib; Haitham Amin; Raul D Santos; Khalid Al-Waili; Khamis Al-Hashmi; Khalid Al-Rasadi
Journal:  Curr Vasc Pharmacol       Date:  2016       Impact factor: 2.719

10.  Prevalence of lipid abnormalities and cholesterol target value attainment in patients with stable coronary heart disease or an acute coronary syndrome in Saudi Arabia.

Authors:  Saud Al Sifri; Owayed Al Shammeri; Saleh Al Jaser; Abdullah Alkhenizan; Atif Bin Shafi Shafiurrehman; Bassem Morcos; Sameh Wajih; Ibrahim Elnahal; Martin Horack; Philippe Brudi; Dominik Lautsch; Baishali Ambegaonkar; Ami Vyas; Carl A Baxter; Anselm K Gitt
Journal:  Saudi Med J       Date:  2018-07       Impact factor: 1.484

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