Literature DB >> 24301185

Pedopeptins, novel inhibitors of LPS: taxonomy of producing organism, fermentation, isolation, physicochemical properties and structural elucidation.

Yuki Hirota-Takahata1, Shiho Kozuma2, Nahoki Kuraya3, Daisuke Fukuda1, Mutsuo Nakajima3, Osamu Ando4.   

Abstract

In the course of our screening for inhibitors of lipopolysaccharide (LPS) binding to cellular receptor CD14, potent inhibitory activity was detected in the cultured broth of Pedobacter sp. SANK 72003. Three active compounds, pedopeptin A, B and C, were isolated from the broth and their structures were elucidated by physicochemical and spectral data to be new cyclic depsipeptides.

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Year:  2013        PMID： 24301185     DOI： 10.1038/ja.2013.122

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  7 in total

1.  Ogipeptins, novel inhibitors of LPS: physicochemical properties and structural elucidation.

Authors:  Yuki Hirota-Takahata; Shiho Kozuma; Nahoki Kuraya; Daisuke Fukuda; Mutsuo Nakajima; Toshio Takatsu; Osamu Ando
Journal:  J Antibiot (Tokyo)       Date:  2016-06-22       Impact factor: 2.649

2.  Taeanamides A and B, Nonribosomal Lipo-Decapeptides Isolated from an Intertidal-Mudflat-Derived Streptomyces sp.

Authors:  Jinsheng Cui; Eunji Kim; Dong Hyun Moon; Tae Ho Kim; Ilnam Kang; Yeonjung Lim; Daniel Shin; Sunghoon Hwang; Young Eun Du; Myoung Chong Song; Munhyung Bae; Jang-Cheon Cho; Jichan Jang; Sang Kook Lee; Yeo Joon Yoon; Dong-Chan Oh
Journal:  Mar Drugs       Date:  2022-06-16       Impact factor: 6.085

3.  Identification and biological activity of ogipeptins, novel LPS inhibitors produced by marine bacterium.

Authors:  Shiho Kozuma; Yuki Hirota-Takahata; Daisuke Fukuda; Nahoki Kuraya; Mutsuo Nakajima; Osamu Ando
Journal:  J Antibiot (Tokyo)       Date:  2016-07-06       Impact factor: 2.649

4.  Alterins Produced by Oyster-Associated Pseudoalteromonas Are Antibacterial Cyclolipopeptides with LPS-Binding Activity.

Authors:  Florie Desriac; Abderrafek El Harras; Matthieu Simon; Arnaud Bondon; Benjamin Brillet; Patrick Le Chevalier; Martine Pugnière; Patrice Got; Delphine Destoumieux-Garzón; Yannick Fleury
Journal:  Mar Drugs       Date:  2020-12-10       Impact factor: 5.118

5.  Selective Isolation of Multidrug-Resistant Pedobacter spp., Producers of Novel Antibacterial Peptides.

Authors:  Joakim Bjerketorp; Jolanta J Levenfors; Christina Nord; Bengt Guss; Bo Öberg; Anders Broberg
Journal:  Front Microbiol       Date:  2021-02-25       Impact factor: 5.640

6.  In-peptide amino acid racemization via inter-residue oxazoline intermediates during acidic hydrolysis.

Authors:  Anders Broberg; Christina Nord; Jolanta J Levenfors; Joakim Bjerketorp; Bengt Guss; Bo Öberg
Journal:  Amino Acids       Date:  2021-02-13       Impact factor: 3.520

7.  Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria.

Authors:  Christina Nord; Joakim Bjerketorp; Jolanta J Levenfors; Sha Cao; Adam A Strömstedt; Bengt Guss; Rolf Larsson; Diarmaid Hughes; Bo Öberg; Anders Broberg
Journal:  ACS Chem Biol       Date:  2020-10-14       Impact factor: 5.100
  7 in total

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