Literature DB >> 24298497

Meningitis Due to Cryptococcus gattii in an Immunocompetent Patient.

Rajesh T Patil1, Jyoti Sangwan, Deepak Juyal, Sumit Lathwal.   

Abstract

The incidence of cryptococcal infection is high in developing countries such as India. Cryptococcus gattii, formerly known as Cryptococcus neoformans var gattii, is an encapsulated yeast that causes disease in both immunocompetent and immunosupressed individuals. The organism enters via respiratory tract and causes a spectrum of illness ranging from asymptomatic infection to severe illness, including pneumonia and disseminated infection involving multiple sites, including the central nervous system, eyes and skin. Cryptococcal meningitis is generally considered as rare in immunocompetent patients; therefore, specific treatment is not implemented until the organism is identified or a cryptococcal antigen is detected. We describe the case of a 30-years-old man without prior medical history who presented with meningitis and was treated successfully. This case illustrates the importance of considering infectious causes such as C.gattii in the differential diagnosis of meningitis, regardless of the patient's immune status.

Entities:  

Keywords:  Amphotericin; Cryptococcus gattii; Immunocompromised; Meningitis

Year:  2013        PMID: 24298497      PMCID: PMC3843417          DOI: 10.7860/JCDR/2013/6770.3492

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  4 in total

1.  Molecular epidemiology of clinical Cryptococcus neoformans strains from India.

Authors:  N Jain; B L Wickes; S M Keller; J Fu; A Casadevall; P Jain; M A Ragan; U Banerjee; B C Fries
Journal:  J Clin Microbiol       Date:  2005-11       Impact factor: 5.948

2.  A fatal case of meningitis caused by Cryptococcus neoformans var. grubii in an immunocompetent male.

Authors:  Prashant Gupta; Shruti Malik; Vineeta Khare; Gopa Banerjee; Anurag Mehrotra; Sanjay Mehrotra; Mastan Singh
Journal:  J Infect Dev Ctries       Date:  2011-02-01       Impact factor: 0.968

3.  Cryptococcal infection in patients with clinically diagnosed meningitis in a tertiary care center.

Authors:  K N Prasad; J Agarwal; V L Nag; A K Verma; A K Dixit; A Ayyagari
Journal:  Neurol India       Date:  2003-09       Impact factor: 2.117

4.  Fluconazole and itraconazole susceptibility of clinical isolates of Cryptococcus neoformans at a tertiary care centre in India: a need for care.

Authors:  K Datta; N Jain; S Sethi; A Rattan; A Casadevall; U Banerjee
Journal:  J Antimicrob Chemother       Date:  2003-09-01       Impact factor: 5.790

  4 in total
  3 in total

1.  Cryptococcal meningitis: An under-reported disease from the hills of Uttarakhand: A hospital-based cross-sectional study.

Authors:  Aroop Mohanty; Mohit Bhatia; Ankita Kabi; Kuhu Chatterjee; Neelam Kaistha; Balram Ji Omar; Puneet K Gupta; Pratima Gupta
Journal:  J Family Med Prim Care       Date:  2019-06

Review 2.  Ecoepidemiology of Cryptococcus gattii in Developing Countries.

Authors:  Patricia F Herkert; Ferry Hagen; Rosangela L Pinheiro; Marisol D Muro; Jacques F Meis; Flávio Queiroz-Telles
Journal:  J Fungi (Basel)       Date:  2017-11-03

Review 3.  Cryptococcosis caused by cryptococcus gattii: 2 case reports and literature review.

Authors:  Xinying Xue; Hui Deng; Longting Zhao; Xuelei Zang; Idorenyin Polycarp Asuquo; Mingming Meng; Xidong Ma; Chong Qin; Yao Meng; Chongchong Wu; Jie Gao; Lei Pan
Journal:  Medicine (Baltimore)       Date:  2020-12-11       Impact factor: 1.817

  3 in total

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