Literature DB >> 24297733

Influence of age, sex and genetic factors on the human brain.

D Reese McKay1, Emma E M Knowles, Anderson A M Winkler, Emma Sprooten, Peter Kochunov, Rene L Olvera, Joanne E Curran, Jack W Kent, Melanie A Carless, Harald H H Göring, Thomas D Dyer, Ravi Duggirala, Laura Almasy, Peter T Fox, John Blangero, David C Glahn.   

Abstract

We report effects of age, age(2), sex and additive genetic factors on variability in gray matter thickness, surface area and white matter integrity in 1,010 subjects from the Genetics of Brain Structure and Function Study. Age was more strongly associated with gray matter thickness and fractional anisotropy of water diffusion in white matter tracts, while sex was more strongly associated with gray matter surface area. Widespread heritability of neuroanatomic traits was observed, suggesting that brain structure is under strong genetic control. Furthermore, our findings indicate that neuroimaging-based measurements of cerebral variability are sensitive to genetic mediation. Fundamental studies of genetic influence on the brain will help inform gene discovery initiatives in both clinical and normative samples.

Entities:  

Mesh：

Year:  2014        PMID： 24297733      PMCID： PMC4011973          DOI： 10.1007/s11682-013-9277-5

Source DB:  PubMed          Journal:  Brain Imaging Behav        ISSN： 1931-7557            Impact factor:   3.978


  35 in total

1.  Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex.

Authors:  B Fischl; A Liu; A M Dale
Journal:  IEEE Trans Med Imaging       Date:  2001-01       Impact factor: 10.048

2.  Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain.

Authors:  Bruce Fischl; David H Salat; Evelina Busa; Marilyn Albert; Megan Dieterich; Christian Haselgrove; Andre van der Kouwe; Ron Killiany; David Kennedy; Shuna Klaveness; Albert Montillo; Nikos Makris; Bruce Rosen; Anders M Dale
Journal:  Neuron       Date:  2002-01-31       Impact factor: 17.173

3.  A hybrid approach to the skull stripping problem in MRI.

Authors:  F Ségonne; A M Dale; E Busa; M Glessner; D Salat; H K Hahn; B Fischl
Journal:  Neuroimage       Date:  2004-07       Impact factor: 6.556

4.  Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturer.

Authors:  Xiao Han; Jorge Jovicich; David Salat; Andre van der Kouwe; Brian Quinn; Silvester Czanner; Evelina Busa; Jenni Pacheco; Marilyn Albert; Ronald Killiany; Paul Maguire; Diana Rosas; Nikos Makris; Anders Dale; Bradford Dickerson; Bruce Fischl
Journal:  Neuroimage       Date:  2006-05-02       Impact factor: 6.556

5.  Sequence-independent segmentation of magnetic resonance images.

Authors:  Bruce Fischl; David H Salat; André J W van der Kouwe; Nikos Makris; Florent Ségonne; Brian T Quinn; Anders M Dale
Journal:  Neuroimage       Date:  2004       Impact factor: 6.556

6.  Geometrically accurate topology-correction of cortical surfaces using nonseparating loops.

Authors:  Florent Ségonne; Jenni Pacheco; Bruce Fischl
Journal:  IEEE Trans Med Imaging       Date:  2007-04       Impact factor: 10.048

7.  Sex differences in brain structure in auditory and cingulate regions.

Authors:  Caroline C Brun; Natasha Leporé; Eileen Luders; Yi-Yu Chou; Sarah K Madsen; Arthur W Toga; Paul M Thompson
Journal:  Neuroreport       Date:  2009-07-01       Impact factor: 1.837

8.  A nonparametric method for automatic correction of intensity nonuniformity in MRI data.

Authors:  J G Sled; A P Zijdenbos; A C Evans
Journal:  IEEE Trans Med Imaging       Date:  1998-02       Impact factor: 10.048

9.  Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system.

Authors:  B Fischl; M I Sereno; A M Dale
Journal:  Neuroimage       Date:  1999-02       Impact factor: 6.556

10.  Measuring and comparing brain cortical surface area and other areal quantities.

Authors:  Anderson M Winkler; Mert R Sabuncu; B T Thomas Yeo; Bruce Fischl; Douglas N Greve; Peter Kochunov; Thomas E Nichols; John Blangero; David C Glahn
Journal:  Neuroimage       Date:  2012-03-15       Impact factor: 6.556
View more
  42 in total

1.  Recurrent major depression and right hippocampal volume: A bivariate linkage and association study.

Authors:  Samuel R Mathias; Emma E M Knowles; Jack W Kent; D Reese McKay; Joanne E Curran; Marcio A A de Almeida; Thomas D Dyer; Harald H H Göring; Rene L Olvera; Ravi Duggirala; Peter T Fox; Laura Almasy; John Blangero; David C Glahn
Journal:  Hum Brain Mapp       Date:  2015-10-20       Impact factor: 5.038

2.  Harmonizing DTI measurements across scanners to examine the development of white matter microstructure in 803 adolescents of the NCANDA study.

Authors:  Kilian M Pohl; Edith V Sullivan; Torsten Rohlfing; Weiwei Chu; Dongjin Kwon; B Nolan Nichols; Yong Zhang; Sandra A Brown; Susan F Tapert; Kevin Cummins; Wesley K Thompson; Ty Brumback; Ian M Colrain; Fiona C Baker; Devin Prouty; Michael D De Bellis; James T Voyvodic; Duncan B Clark; Claudiu Schirda; Bonnie J Nagel; Adolf Pfefferbaum
Journal:  Neuroimage       Date:  2016-02-10       Impact factor: 6.556

3.  Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index.

Authors:  Karen Hodgson; Russell A Poldrack; Joanne E Curran; Emma E Knowles; Samuel Mathias; Harald H H Göring; Nailin Yao; Rene L Olvera; Peter T Fox; Laura Almasy; Ravi Duggirala; Deanna M Barch; John Blangero; David C Glahn
Journal:  Cereb Cortex       Date:  2017-12-01       Impact factor: 5.357

4.  A Comprehensive Quantitative Genetic Analysis of Cerebral Surface Area in Youth.

Authors:  J Eric Schmitt; Michael C Neale; Liv S Clasen; Siyuan Liu; Jakob Seidlitz; Joshua N Pritikin; Alan Chu; Gregory L Wallace; Nancy Raitano Lee; Jay N Giedd; Armin Raznahan
Journal:  J Neurosci       Date:  2019-03-04       Impact factor: 6.167

5.  Cortical complexity as a measure of age-related brain atrophy.

Authors:  Christopher R Madan; Elizabeth A Kensinger
Journal:  Neuroimage       Date:  2016-04-19       Impact factor: 6.556

6.  Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology.

Authors:  Josephine Mollon; Joanne E Curran; Samuel R Mathias; Emma E M Knowles; Phoebe Carlisle; Peter T Fox; Rene L Olvera; Harald H H Göring; Amanda Rodrigue; Laura Almasy; Ravi Duggirala; John Blangero; David C Glahn
Journal:  Diabetologia       Date:  2020-02-04       Impact factor: 10.122

7.  Human Cortical Thickness Organized into Genetically-determined Communities across Spatial Resolutions.

Authors:  Aaron F Alexander-Bloch; Samuel R Mathias; Peter T Fox; Rene L Olvera; Harold H H Göring; Ravi Duggirala; Joanne E Curran; John Blangero; David C Glahn
Journal:  Cereb Cortex       Date:  2019-01-01       Impact factor: 5.357

8.  Adolescent Development of Cortical and White Matter Structure in the NCANDA Sample: Role of Sex, Ethnicity, Puberty, and Alcohol Drinking.

Authors:  Adolf Pfefferbaum; Torsten Rohlfing; Kilian M Pohl; Barton Lane; Weiwei Chu; Dongjin Kwon; B Nolan Nichols; Sandra A Brown; Susan F Tapert; Kevin Cummins; Wesley K Thompson; Ty Brumback; M J Meloy; Terry L Jernigan; Anders Dale; Ian M Colrain; Fiona C Baker; Devin Prouty; Michael D De Bellis; James T Voyvodic; Duncan B Clark; Beatriz Luna; Tammy Chung; Bonnie J Nagel; Edith V Sullivan
Journal:  Cereb Cortex       Date:  2015-09-26       Impact factor: 5.357

9.  Genetic Complexity of Cortical Structure: Differences in Genetic and Environmental Factors Influencing Cortical Surface Area and Thickness.

Authors:  Lachlan T Strike; Narelle K Hansell; Baptiste Couvy-Duchesne; Paul M Thompson; Greig I de Zubicaray; Katie L McMahon; Margaret J Wright
Journal:  Cereb Cortex       Date:  2019-03-01       Impact factor: 5.357

10.  Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium.

Authors:  Xiang-Zhen Kong; Samuel R Mathias; Tulio Guadalupe; David C Glahn; Barbara Franke; Fabrice Crivello; Nathalie Tzourio-Mazoyer; Simon E Fisher; Paul M Thompson; Clyde Francks
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-15       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.