Literature DB >> 24297622

Negative symptoms mediate the influence of theory of mind on functional status in schizophrenia.

Urvakhsh Meherwan Mehta1, Jagadisha Thirthalli, Channaveerachari Naveen Kumar, J Keshav Kumar, Bangalore N Gangadhar.   

Abstract

We aimed to assess the relationship between social cognition, neurocognition, negative symptoms and functional status in a homogeneous schizophrenia patient group remitted from positive symptoms. Sixty patients underwent assessments of social and neurocognition dimensions recommended by expert panels. A blind rater assessed their functional status. Second order theory of mind (ToM) and negative symptoms had significant correlations with functional status. A bootstrapping analysis used to test for specific mediation models revealed that the effect of second order ToM on functioning was mediated by negative symptoms. Future studies should examine if targeted remediation of ToM improves negative symptoms and thus functioning.

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Year:  2013        PMID： 24297622     DOI： 10.1007/s00127-013-0804-x

Source DB:  PubMed          Journal:  Soc Psychiatry Psychiatr Epidemiol        ISSN： 0933-7954            Impact factor:   4.328


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