BACKGROUND: Because hypertension and depression share common pathways, it is possible that each disease has an impact on the natural history of the other. OBJECTIVE: To determinate whether depression influences blood pressure control in hypertensive patients. METHODS: Forty hypertensive patients undergoing antihypertensive treatment, excluding beta-blockers and central-acting agents, self-measured their blood pressure several times a day for three days using a validated, commercially available device. All patients also completed the Zung Self-rating Depression Scale survey for depression. Associations between the results of the blood pressure and depression tests were determined using the Spearman correlation coefficient; RR was also measured. RESULTS: Of the 40 patients, 23 were depressed, and 21 of these 23 had poor control of their blood pressure. The RR for uncontrolled hypertension in depressed patients was 15.5. A significant correlation between systolic (r=0.713) and diastolic (r=0.52) blood pressure values and depression was found. CONCLUSION: Depression is common in patients with uncontrolled hypertension and may interfere with blood pressure control. Screening for depression in hypertensive patients is a simple and cost-effective tool that may improve outcomes.
BACKGROUND: Because hypertension and depression share common pathways, it is possible that each disease has an impact on the natural history of the other. OBJECTIVE: To determinate whether depression influences blood pressure control in hypertensivepatients. METHODS: Forty hypertensivepatients undergoing antihypertensive treatment, excluding beta-blockers and central-acting agents, self-measured their blood pressure several times a day for three days using a validated, commercially available device. All patients also completed the Zung Self-rating Depression Scale survey for depression. Associations between the results of the blood pressure and depression tests were determined using the Spearman correlation coefficient; RR was also measured. RESULTS: Of the 40 patients, 23 were depressed, and 21 of these 23 had poor control of their blood pressure. The RR for uncontrolled hypertension in depressedpatients was 15.5. A significant correlation between systolic (r=0.713) and diastolic (r=0.52) blood pressure values and depression was found. CONCLUSION:Depression is common in patients with uncontrolled hypertension and may interfere with blood pressure control. Screening for depression in hypertensivepatients is a simple and cost-effective tool that may improve outcomes.
Authors: Michael P Pignone; Bradley N Gaynes; Jerry L Rushton; Catherine Mills Burchell; C Tracy Orleans; Cynthia D Mulrow; Kathleen N Lohr Journal: Ann Intern Med Date: 2002-05-21 Impact factor: 25.391
Authors: Amanda J Shallcross; Zoe T Duberstein; Sarah H Sperber; Pallavi D Visvanathan; Samina Lutfeali; Nathaniel Lu; James Carmody; Tanya M Spruill Journal: Cogn Behav Pract Date: 2021-02-10
Authors: F Z Marques; N Eikelis; R G Bayles; E A Lambert; N E Straznicky; D Hering; M D Esler; G A Head; D A Barton; M P Schlaich; G W Lambert Journal: Mol Psychiatry Date: 2016-04-05 Impact factor: 15.992