Literature DB >> 24293125

Faith-based perspectives on the use of chimeric organisms for medical research.

Chris Degeling1, Rob Irvine, Ian Kerridge.   

Abstract

Efforts to advance our understanding of neurodegenerative diseases involve the creation chimeric organisms from human neural stem cells and primate embryos--known as prenatal chimeras. The existence of potential mentally complex beings with human and non-human neural apparatus raises fundamental questions as to the ethical permissibility of chimeric research and the moral status of the creatures it creates. Even as bioethicists find fewer reasons to be troubled by most types of chimeric organisms, social attitudes towards the non-human world are often influenced by religious beliefs. In this paper scholars representing eight major religious traditions provide a brief commentary on a hypothetical case concerning the development and use of prenatal human-animal chimeric primates in medical research. These commentaries reflect the plurality and complexity within and between religious discourses of our relationships with other species. Views on the moral status and permissibility of research on neural human animal chimeras vary. The authors provide an introduction to those who seek a better understanding of how faith-based perspectives might enter into biomedical ethics and public discourse towards forms of biomedical research that involves chimeric organisms.

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Year:  2013        PMID: 24293125     DOI: 10.1007/s11248-013-9770-z

Source DB:  PubMed          Journal:  Transgenic Res        ISSN: 0962-8819            Impact factor:   2.788


  15 in total

1.  Biotechnology and monstrosity. Why we should pay attention to the "yuk factor".

Authors:  M Midgley
Journal:  Hastings Cent Rep       Date:  2000 Sep-Oct       Impact factor: 2.683

2.  It is ethical to transplant human stem cells into nonhuman embryos.

Authors:  Phillip Karpowicz; Cynthia B Cohen; Derek van der Kooy
Journal:  Nat Med       Date:  2004-04       Impact factor: 53.440

3.  Ethics: Moral issues of human-non-human primate neural grafting.

Authors:  Mark Greene; Kathryn Schill; Shoji Takahashi; Alison Bateman-House; Tom Beauchamp; Hilary Bok; Dorothy Cheney; Joseph Coyle; Terrence Deacon; Daniel Dennett; Peter Donovan; Owen Flanagan; Steven Goldman; Henry Greely; Lee Martin; Earl Miller; Dawn Mueller; Andrew Siegel; Davor Solter; John Gearhart; Guy McKhann; Ruth Faden
Journal:  Science       Date:  2005-07-15       Impact factor: 47.728

4.  At the edge of humanity: human stem cells, chimeras, and moral status.

Authors:  Robert Streiffer
Journal:  Kennedy Inst Ethics J       Date:  2005-12

5.  Chimeras and human dignity.

Authors:  Inmaculada de Melo-Martín
Journal:  Kennedy Inst Ethics J       Date:  2008-12

6.  Metaphysical and ethical perspectives on creating animal-human chimeras.

Authors:  Jason T Eberl; Rebecca A Ballard
Journal:  J Med Philos       Date:  2009-08-19

7.  Reframing the ethical issues in part-human animal research: the unbearable ontology of inexorable moral confusion.

Authors:  Matthew H Haber; Bryan Benham
Journal:  Am J Bioeth       Date:  2012       Impact factor: 11.229

8.  Human-animal chimeras for vaccine development: an endangered species or opportunity for the developing world?

Authors:  Anant Bhan; Peter A Singer; Abdallah S Daar
Journal:  BMC Int Health Hum Rights       Date:  2010-05-19

9.  What does the British public think about human-animal hybrid embryos?

Authors:  David A Jones
Journal:  J Med Ethics       Date:  2009-03       Impact factor: 2.903

10.  Anticipatory Governance: Bioethical Expertise for Human/Animal Chimeras.

Authors:  Alison Harvey; Brian Salter
Journal:  Sci Cult (Lond)       Date:  2012-02-21
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