Laura Bravo1, Raquel Mateos1, Beatriz Sarriá2, Gema Baeza1, Elena Lecumberri1, Sonia Ramos1, Luis Goya1. 1. Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), C/José Antonio Novais 10, 28040 Madrid, Spain. 2. Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), C/José Antonio Novais 10, 28040 Madrid, Spain. Electronic address: beasarria@ictan.csic.es.
Abstract
OBJECTIVE: To study the effect of mate (Ilex paraguariensis) on serum lipids and antioxidant status in normocholesterolaemic and hypercholesterolaemic rats. METHODS: Triglycerides (TG), total, LDL- and HDL-cholesterol levels, total antioxidant capacity (FRAP and ABTS assays), malondialdehyde (MDA) and protein carbonyls were analysed in serum, and MDA, glutathione and antioxidant enzyme activity in livers of rats drinking water or mate fed normal or cholesterol-cholic supplemented diets. RESULTS: ABTS, glutathione and antioxidant enzymes were not affected by any treatment. In normocholesterolaemic animals, mate had no effect on serum lipids or antioxidant status, yet it increased serum carbonyls and liver MDA concentrations. In hypercholesterolaemic rats, mate consumption had no effect on HDL-cholesterol or protein carbonyls, yet it showed a marked hypolipidaemic action, decreasing TG, total and LDL-cholesterol, and serum MDA levels that had been increased after consuming the high-cholesterol diet. CONCLUSION: Potential beneficial effect of mate on markers of cardiovascular risk seems to be restricted to hyperlipaemic animals.
OBJECTIVE: To study the effect of mate (Ilex paraguariensis) on serum lipids and antioxidant status in normocholesterolaemic and hypercholesterolaemic rats. METHODS:Triglycerides (TG), total, LDL- and HDL-cholesterol levels, total antioxidant capacity (FRAP and ABTS assays), malondialdehyde (MDA) and protein carbonyls were analysed in serum, and MDA, glutathione and antioxidant enzyme activity in livers of rats drinking water or mate fed normal or cholesterol-cholic supplemented diets. RESULTS:ABTS, glutathione and antioxidant enzymes were not affected by any treatment. In normocholesterolaemic animals, mate had no effect on serum lipids or antioxidant status, yet it increased serum carbonyls and liver MDA concentrations. In hypercholesterolaemic rats, mate consumption had no effect on HDL-cholesterol or protein carbonyls, yet it showed a marked hypolipidaemic action, decreasing TG, total and LDL-cholesterol, and serum MDA levels that had been increased after consuming the high-cholesterol diet. CONCLUSION: Potential beneficial effect of mate on markers of cardiovascular risk seems to be restricted to hyperlipaemic animals.
Authors: Sara Fernández-Castillejo; Rosa-Maria Valls; Olga Castañer; Laura Rubió; Úrsula Catalán; Anna Pedret; Alba Macià; Maureen L Sampson; María-Isabel Covas; Montserrat Fitó; Maria-José Motilva; Alan T Remaley; Rosa Solà Journal: Mol Nutr Food Res Date: 2016-05-06 Impact factor: 5.914
Authors: Natalia Pachura; Robert Kupczyński; Jordan Sycz; Agata Kuklińska; Anna Zwyrzykowska-Wodzińska; Katarzyna Wińska; Aleksandra Owczarek; Piotr Kuropka; Renata Nowaczyk; Przemysław Bąbelewski; Antoni Szumny Journal: Foods Date: 2021-12-25