Literature DB >> 24290771

Brain creatine depletion in vegetarians? A cross-sectional ¹H-magnetic resonance spectroscopy (¹H-MRS) study.

Marina Yazigi Solis1, Vítor de Salles Painelli2, Guilherme Giannini Artioli1, Hamilton Roschel1, Maria Concepción Otaduy3, Bruno Gualano1.   

Abstract

The present cross-sectional study aimed to examine the influence of diet on brain creatine (Cr) content by comparing vegetarians with omnivores. Brain Cr content in the posterior cingulate cortex was assessed by proton magnetic resonance spectroscopy (¹H-MRS). Dietary Cr intake was assessed by 3 d food recalls. Vegetarians had lower dietary Cr intake than omnivores (0.03 (SD 0.01) v. 1.34 (SD 0.62) g/d, respectively; P=0.005). However, vegetarians and omnivores had comparable brain total Cr content (5.999 (SD 0.811) v. 5.917 (SD 0.665) IU, respectively; P=0.77). In conclusion, dietary Cr did not influence brain Cr content in healthy individuals, suggesting that in normal conditions brain is dependent on its own Cr synthesis.

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Year:  2013        PMID: 24290771     DOI: 10.1017/S0007114513003802

Source DB:  PubMed          Journal:  Br J Nutr        ISSN: 0007-1145            Impact factor:   3.718


  8 in total

Review 1.  A Role for Data Science in Precision Nutrition and Early Brain Development.

Authors:  Sarah U Morton; Brian J Leyshon; Eleonora Tamilia; Rutvi Vyas; Michaela Sisitsky; Imran Ladha; John B Lasekan; Matthew J Kuchan; P Ellen Grant; Yangming Ou
Journal:  Front Psychiatry       Date:  2022-06-23       Impact factor: 5.435

2.  Effects of beta-alanine supplementation on brain homocarnosine/carnosine signal and cognitive function: an exploratory study.

Authors:  Marina Yazigi Solis; Simon Cooper; Ruth M Hobson; Guilherme G Artioli; Maria C Otaduy; Hamilton Roschel; Jacques Robertson; Daniel Martin; Vitor S Painelli; Roger C Harris; Bruno Gualano; Craig Sale
Journal:  PLoS One       Date:  2015-04-14       Impact factor: 3.240

3.  Creatine target engagement with brain bioenergetics: a dose-ranging phosphorus-31 magnetic resonance spectroscopy study of adolescent females with SSRI-resistant depression.

Authors:  Douglas G Kondo; Lauren N Forrest; Xianfeng Shi; Young-Hoon Sung; Tracy L Hellem; Rebekah S Huber; Perry F Renshaw
Journal:  Amino Acids       Date:  2016-02-23       Impact factor: 3.520

Review 4.  Benefits of Creatine Supplementation for Vegetarians Compared to Omnivorous Athletes: A Systematic Review.

Authors:  Mojtaba Kaviani; Keely Shaw; Philip D Chilibeck
Journal:  Int J Environ Res Public Health       Date:  2020-04-27       Impact factor: 3.390

Review 5.  Creatine Supplementation and Brain Health.

Authors:  Hamilton Roschel; Bruno Gualano; Sergej M. Ostojic; Eric S. Rawson
Journal:  Nutrients       Date:  2021-02-10       Impact factor: 5.717

Review 6.  The Impact of Vegan and Vegetarian Diets on Physical Performance and Molecular Signaling in Skeletal Muscle.

Authors:  Alexander Pohl; Frederik Schünemann; Käthe Bersiner; Sebastian Gehlert
Journal:  Nutrients       Date:  2021-10-29       Impact factor: 5.717

7.  Central nervous system uptake of intranasal glutathione in Parkinson's disease.

Authors:  Laurie K Mischley; Kevin E Conley; Eric G Shankland; Terrance J Kavanagh; Michael E Rosenfeld; John E Duda; Collin C White; Timothy K Wilbur; Prysilla U De La Torre; Jeannie M Padowski
Journal:  NPJ Parkinsons Dis       Date:  2016-02-25

Review 8.  Potential for use of creatine supplementation following mild traumatic brain injury.

Authors:  Philip John Ainsley Dean; Gozdem Arikan; Bertram Opitz; Annette Sterr
Journal:  Concussion       Date:  2017-03-21
  8 in total

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